Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22524 Idelalisib GSE70138 HUES3 Human 24h 1.11uM EID0040
Types Number Response transcription factors
Up-regulation 154 VGLL4; PAX8; EZH2; SMARCD1; RELB; WIZ; CALCOCO1; VPS72; IKBKAP; ZMIZ2; SIN3B; MSC; OSR2; AR; KDM5A; ARID1A; NR5A2; IRF9; MED23; MEN1; MED24; ZNF224; UBTF; FEZF2; SAFB; THRA; HDAC7; CRTC1; LZTR1; TLX3; HOXB6; RING1; SUB1; HOXA11; JAK2; FOXA2; PBXIP1; NAB2; CNOT2; ASXL1; ZNF576; MYF6; ZNF227; MED13; ZBTB7A; RUNX3; CD3D; ZNF350; HOXB2; SUPT4H1; PAXBP1; ZNF516; HMGB1; BATF3; MKL2; FOXK2; KLF1; RFX7; TRIB3; CBX7; STAT6; TEAD3; SMARCA2; NKX3-2; BCL3; NOC2L; E4F1; FOXL2; ETV7; MITF; MED15; PTRF; ATF7IP; CERS4; WT1; IRF8; MEIS2; NFE2L3; ZBED2; SIRT7; PSMC3; ILF2; ZNF266; MYRF; SP2; HOXB13; SIX2; ALX1; ZNF589; MED1; PLAGL2; SOX9; HDGF; NFE2L1; KDM4C; HOXB5; TFAP2C; ZEB1; NR2F2; SSBP3; FOSL2; AFF1; KLF4; RXRA; ARL2BP; ZNF45; ZNF267; NFAT5; SMARCC2; CUX2; FOXD1; TULP3; FOXF2; SOX13; BCL11A; CBX6; SSX1; EMX2; HIRA; PBX1; IRF6; ZNF12; TFEC; TFAP2A; BTG1; SHOX2; KAT2B; SIAH2; NCOA2; SNIP1; APEX1; CITED2; HMBOX1; EGR3; RORA; HIC2; TOB1; ARID5B; TRPS1; TGFB1I1; IRF4; NPAS2; ESR1; HMG20B; NR4A2; GRHL2; MEIS1; TWIST1; ARNT2; MYBL1; LEF1; TBX3; E2F2; TXNIP
Down-regulation 74 SMARCC1; CCNA2; SUPT3H; CCNH; CNBP; INSR; CHD7; CBFB; E2F3; MLLT10; NR1D2; HLTF; HSBP1; TFDP1; CDYL; RYBP; NKX2-2; BRD7; GTF3A; ING1; KLF11; RNF138; TSC22D2; PIAS2; ZEB2; C1QBP; INSM1; BCL10; CCNE1; SOX11; ZNF165; KLF7; TAF10; TCF7L1; LIN28A; ZNF3; PMS1; TAF7; PBX3; SATB2; ZNF93; DNMT3B; TFDP2; PHF20; HOXD1; FOXO1; TCEB2; TTF1; ZNF573; SMARCA1; ZNF281; ELK3; LYL1; EDF1; BAZ1A; KLF2; ZNF302; ASCL1; ERG; ELF5; ETV5; SP110; IL16; ZNF430; PEG3; NKX2-1; NFIB; ID4; MECOM; HEY1; ISL1; DACH1; MAFB; HOXC6