Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22503 Osimertinib GSE70138 HUES3 Human 24h 0.04uM EID0040
Types Number Response transcription factors
Up-regulation 25 HOXA10; ZIC1; NFKB1; TRIB3; NKX2-2; SHOX2; TTF1; ZEB2; BHLHE41; HOXB7; INSM1; HOXC10; RUNX3; FOSL1; HOXA5; KLF6; ZFHX4; FLNA; KDM5D; ZBTB38; FOXF1; FOXG1; HOXC6; HOXB2; PPARG
Down-regulation 26 CREB3L2; ZNF304; TLE1; RERE; CCNE1; ZFP36L2; SRCAP; STAT6; FOXO1; TCF7L1; HLF; SUB1; CEBPB; SMAD6; FOXC1; RXRA; TOB1; TRIM22; CITED2; ERBB4; ELF5; RBPMS; ST18; TXNIP; MAFB; ARNT2