Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22499 Osimertinib GSE70138 HUES3 Human 24h 3.33uM EID0040
Types Number Response transcription factors
Up-regulation 19 AHR; KLF6; ZNF350; CTBP2; TGIF1; ZNF329; HTATIP2; ELF3; SMAD2; HMGB2; CRY1; CUX2; TOB1; TOX; ZNF217; SOX9; MEIS2; TSC22D1; NKX3-1
Down-regulation 26 ERBB2; IKBKAP; RUVBL1; EZH2; COPS2; ZIC1; RREB1; SND1; ATF4; MAZ; MED24; RYBP; CNBP; FOXN3; APEX1; HMG20B; CREB1; MED1; CREB3L2; PBX3; NFIB; EN1; TXNIP; HOXB2; HOXC6; POU2AF1