Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22314 Gsk-1059615 GSE70138 ASC Human 24h 10uM EID0027
Types Number Response transcription factors
Up-regulation 83 HOXA5; FOXO4; HDAC4; TCFL5; CBX7; HTATIP2; KDM2A; RXRA; TSC22D3; CEBPZ; ARID4A; TGIF1; ZBTB7A; STAT6; PNRC1; DPF2; NR0B1; TCF25; USF2; CEBPA; LDB1; PHF1; PURA; FOSB; PATZ1; NUP62; MTA1; NCOA6; CREBL2; HIVEP2; DEAF1; KLF6; BRD3; PBXIP1; FOXN3; SUPT3H; KLF11; ZMIZ2; ING3; AFF1; IRF1; CITED2; FLNA; AATF; CARHSP1; HOXB7; NAB1; NCOR2; TOB1; CBX6; HBP1; TULP4; KLF5; CTBP1; YBX3; BAZ2B; HOXC6; BCL11A; HOXA10; KLF13; PBX1; TAF10; SATB1; NPAS2; ARID5B; MYCL; LEF1; BMI1; MAFB; SPEN; SOX9; TP63; TBX3; FOXC1; KDM5D; BASP1; TFAP2C; HOXB6; TSC22D1; HOXD1; MAF; THAP11; MXI1
Down-regulation 96 ZNF274; ZNF606; ZNF268; SMAD7; RUVBL1; PEG3; ZNF10; MEIS2; HIPK2; ISL1; FOXA2; ESRRG; RCOR3; ZBTB16; MECOM; ZNF334; WT1; HAND1; WWC1; CREB5; CALR; GTF3A; AR; TCEA1; PKNOX2; NRBF2; AFF4; HMBOX1; TEAD1; TULP3; ZNF415; SP140; NANOG; PSIP1; CBFB; ZSCAN9; NR4A3; MEOX1; NCOA4; DDX5; LPIN2; PAX5; GTF2I; FOXM1; MYBL1; ZNF512B; MYT1L; BHLHE40; BRIP1; HLF; RARA; TRIM24; ZNF43; EPAS1; ZSCAN16; ZNF419; ZFHX4; ASH2L; ATF3; PHOX2B; ASCL1; NPM1; MEOX2; SIX3; ID4; NKX2-1; CITED1; SOX11; LOXL2; ZNF134; EHF; NR4A1; ELF5; MSX1; SMAD1; ID3; XBP1; PRRX1; PLAGL1; MEIS1; TCF21; ZNF304; NFIB; HMGN3; EGR3; MAGED1; HHEX; DAXX; PITX1; GATA6; ESR1; ID1; E2F2; MTF2; ZNF586; IKZF1