Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22293 Ibrutinib GSE70138 ASC Human 24h 0.37uM EID0027
Types Number Response transcription factors
Up-regulation 38 ZNF589; KDM2A; HIVEP1; KAT6B; ADRB2; NFKBIA; MYC; DNMT3B; YWHAB; CCDC59; CHD3; NUP62; STAT6; FOSL1; PIR; FLNA; DDIT3; ZMYND8; CENPF; PIAS2; RORA; RBPMS; SATB1; AFF1; HMGA1; PPARG; SAP30; RFX5; KDM5D; MAF; KLF2; ZIC1; HMGA2; NFIB; BASP1; MAGED1; THAP11; RELB
Down-regulation 94 ARNT2; ZNF177; ZNF223; MAK; ZNF117; ZNF155; ZNF345; ZNF180; NFE2L2; PRPF6; TRIB3; ELF3; NR1H4; GMNN; PRDM12; ZSCAN9; CARF; ZNF215; EHF; ZNF667; ZBED2; KLF1; TAL1; PQBP1; ERBB4; ZNF467; AEBP1; ZSCAN16; ZFPM2; ZNF665; SP140; CHD4; ZNF224; CAMTA1; MNDA; NEUROD1; NR5A2; TLE2; ZNF91; ZNF136; RARG; ZNF83; OSR2; LYL1; CBFA2T3; DLX2; ST18; KLF13; CREB3; DAXX; CTBP2; SIX3; PRRX1; PAWR; JUP; ZNF711; ID4; WWC1; TCF7L2; ZNF512B; PITX2; NFE2; MYRF; PSMC3; CRYM; BACH2; ZNF544; CNOT3; KLF4; EMX2; MYCL; TFEC; HOXD1; ZSCAN31; ZNF264; ID3; ZBTB38; INSM1; PAX6; NFAT5; HMGN3; MYBL1; GATA6; ZSCAN18; RUNX1; SMAD1; ZBTB20; MEOX2; IFI16; DACH1; DNMT1; MTF2; ID1; CREB1