Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22241 Tivozanib GSE70138 ASC Human 24h 1.11uM EID0027
Types Number Response transcription factors
Up-regulation 29 TBPL1; HOXC10; CITED2; HMGA2; RORA; FOXA1; LEF1; DDX17; KLF9; ZMYND8; HEY1; IKZF1; TCF7; TRIM32; DNAJC1; DNMT3B; BRD4; MAGED1; ID1; HDAC1; ZNF721; TXNIP; RBL2; AFF1; NKX3-1; TGFB1; SMARCA1; PIR; THAP11
Down-regulation 63 TEAD1; PROX1; ZNF93; ZNF443; WNT4; MLLT10; TFEC; TSC22D2; ERBB2; BAZ1A; ZFP36L2; ZNF140; NR4A1; ZIC3; ZNF667; ZNF268; HESX1; SP140; ZNF85; TAF1A; FOXL2; GATAD2A; NANOG; PHOX2B; ZKSCAN7; MYCN; DEK; BRIP1; EMX2; NR4A3; EGR4; OSR2; MNDA; PEG3; HIPK1; ANKRD1; CTBP2; ZEB1; ST18; TFAP2C; FOSL1; TCF7L2; ZNF91; IRF6; SOX17; ZBED2; ABL1; YBX3; EN1; TRIM22; ZNF551; MYBL1; HOXD3; ATF3; DACH1; HOXD1; TOX3; NFATC3; NFE2; WT1; ZNF423; ZBTB18; ESR1