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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22232 Mitoxantrone GSE70138 ASC Human 24h 10uM EID0027
Types Number Response transcription factors
Up-regulation 139 PAX8; FOXM1; NOC2L; E2F4; NR0B2; HOXC11; MECOM; IRF6; PROP1; ZNF507; HIPK2; LHX6; NHLH1; ADRB2; HOXC5; ZBTB44; PRDM14; SSX3; HMGXB3; IKZF2; ZNF710; MYCL; WDR77; THRB; TFAP2A; E2F1; DCC; CDK2; SIM2; ZNF324; SLC2A4RG; ACTL6A; ERBB4; CCNA2; SSX1; ETV1; BCL11A; SOHLH2; RING1; CBFA2T2; NEUROD2; HMGA1; EYA1; PAX1; LDB1; HOXB5; SUMO1; PBX3; HINFP; ZNF75D; ZNF253; WNT4; MYBL2; ARNTL2; ZNF250; TCF7; CDK8; ING4; ZNF93; LHX3; ARL2BP; NFIX; ALX1; DACH1; GRHL2; ZNF816; ELK4; NFATC3; MXD4; HMGB1; NR1H2; CTNNB1; ATOH1; TAF4B; NFE2L3; PHF1; MYBL1; CNBP; ZNF200; GCFC2; ZNF665; ZNF667; ZNF623; SOX5; HOXB13; ZNF532; URI1; TRPS1; BCL11B; SOX17; ZMYND11; BACH2; HOXA11; ZNF551; FOXF1; INSM1; KLF7; TFDP1; ZNF107; FOS; PAWR; PHOX2B; VGLL1; ZNF264; LEF1; ZNF654; ETS1; PAX6; NANOG; TRIM29; TRIB3; EPAS1; MEOX1; ZNF467; WWC1; PRRX1; DAXX; ZSCAN18; HDAC9; ZKSCAN1; GATA2; STAT4; ZEB1; TCF4; ISL1; FOSB; IFI16; YBX1; ZBED2; EMX2; THAP11; SPIB; MEIS2; ELK3; ZNF423; RFX5; TWIST1; TXNIP; ID1
Down-regulation 144 CDK7; NFIL3; NFKBIA; MYC; FHL2; ERBB2; CEBPB; VGLL4; XBP1; TBP; KAT6A; CTR9; NUP62; ADNP; KDM5B; TLE1; PHIP; TSC22D3; NRIP1; TAF9; CEBPA; RNF4; SCAND1; RNF111; SNW1; ARID4B; ZBTB11; FOXO3; HDAC6; TLE4; CEBPG; CCDC59; SERTAD2; KDM2A; MED1; PLAGL2; FOXJ3; EGR2; DPF2; NRBF2; BCL10; MEF2A; BRPF1; DNAJC2; BATF; RLF; DDIT3; CEBPD; SOX4; TSC22D2; KLF9; CHD1; ITGB3BP; CARM1; PPRC1; KAT7; FOSL2; ZBTB16; PPARGC1A; ZNF12; MNT; CENPB; BHLHE40; ELF4; MED6; NCOA6; MTDH; EGR3; THAP1; ZNF14; AATF; ELF1; IRX5; ID2; RREB1; ZNF84; ATF4; MED23; DDX17; ZBTB1; TSG101; VEZF1; COPS2; NCOA4; TAF1D; TRIP6; FOXO1; SIX1; TBL1X; SAP30; KAT8; MAFB; PURA; HLTF; KLF2; ZNF267; POLR2A; NFE2L1; SSBP2; SMAD7; ZNF146; NR1H3; BCL3; ZBTB38; SPEN; CHD9; IKBKAP; TAF10; JUNB; BTG1; ZMYND8; PHF20; JARID2; FOSL1; PUF60; FLNA; APEX1; ID3; NR2F2; SALL1; TRIM22; NCOA2; BCL6; RBBP7; RUNX1; PEG3; EED; ZNF217; STAT5B; MAFF; PBX1; NR1D2; SMAD3; KLF10; KLF4; PIR; AHR; HHEX; BASP1; NR4A2; CITED2; KDM5D; SUV39H1; TBX2
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