Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22220 Nvp-bgj398 GSE70138 ASC Human 24h 3.33uM EID0026
Types Number Response transcription factors
Up-regulation 259 MEF2C; ADRB2; EZH2; ERBB4; IKZF2; ORC2; STAT5B; LHX1; TBPL1; SOX17; ZBTB39; GATA3; POU6F1; HNF4A; USP16; IRF5; STAT5A; BARX2; CARF; ZIM2; FLI1; PRDM1; TRIM25; EYA3; IKZF4; JAK2; NKRF; HIPK3; RAX; ZNF34; ADNP2; PAX8; GFI1; TAF1C; ZNF507; TP63; HAND1; NR6A1; CBL; MAFK; SSBP3; SOX15; BATF; ETV6; TBX4; SNIP1; TRRAP; ZNF235; RFX7; MYF6; ZNF324B; SSX1; BLM; POU3F4; NKX6-1; POU3F2; MYOG; TLX3; WDHD1; ZBTB32; MYOD1; CREB3L2; ZNF175; PAX9; TRAF6; BRDT; GCM1; MYBBP1A; ZNF221; WHSC1L1; TONSL; KLF15; ELF5; IFNB1; ZNF155; AIRE; HEY2; ZNF273; CASZ1; GATA4; ZNF480; YBX2; RUNX2; KLF4; ETV7; PSMC3IP; HDAC1; WNT4; RFX2; ZNF816; TULP2; DNAJC1; HDAC9; HIVEP3; ZSCAN5A; ZNF835; SP4; GBX2; FOXL2; HOXA1; FOXC1; ZNF267; APBB1; ZNF10; LMCD1; GABPA; THRA; PAXBP1; TFEC; HES2; SOX3; FOXN2; TBR1; CCNT1; TCF15; SRY; ZNF14; PHOX2A; HNF1B; TFAP2B; SPEN; HIF3A; CHAF1B; NFE2L3; ZNF132; EMX1; NHLH2; HESX1; FOXI1; SIX6; SOX14; GBX1; KDM2A; LDB1; RFX3; ZNF254; ZIC3; ZNF205; PROX1; CEBPE; TBX21; POU2F2; ZFPM2; CHD2; ETV3; MYCN; EGR3; RUNX3; OSR2; IRF6; ZNF225; RNF138; IRF4; HIC2; ONECUT2; MYT1L; ELF3; CREB3L1; ZFY; BRCA2; MYT1; ANKRD1; BNC1; HOXA7; CHD1; ETV4; POU1F1; PRDM12; ZNF529; ZNF124; PITX2; TFCP2L1; SMAD3; TRAK1; HSF2; BAZ2A; MAFF; IKZF5; SOX10; ZHX3; ZBTB43; PLAGL1; POLR2A; NKX3-1; TBX2; CERS4; YAF2; SP140; ZNF671; MYCL; MSC; NFE2; BMI1; PHOX2B; CALR; SOX13; RNF141; MNX1; YEATS4; HMGA1; SIM1; ARID1A; NR0B1; AHR; IRF8; BHLHE40; SUB1; KAT7; PCGF2; ZNF443; NPAS2; TAF1D; PIR; TBL1XR1; DLX5; GTF2I; OLIG2; HOXA10; BATF3; TCF7L2; KLF2; CBX3; HHEX; CRYM; ETS2; CREM; BACH1; ZBTB20; HMGA2; IFI16; LIN28A; TOX3; ID4; SOX9; HOXD1; RB1; BHLHE41; NFAT5; STAT4; EHF; IRF1; ELK3; ERG; ZBTB16; SP140L; PEG3; ZBED2; TCF21; ZNF117; TRIP6; CITED2; RBPMS; MXI1; GATA6; MAF; TSC22D1; ATF3; ZEB2; EMX2
Down-regulation 106 ERBB2; PDLIM1; TSC22D3; CLOCK; EDF1; BACH2; AES; LEF1; ZFP36L1; MAML1; CHD9; BRD2; SHOX2; BRD7; ZNF148; CUX1; MZF1; ZNF354A; COPS5; DEK; CEBPD; NRBF2; GMEB2; CTBP1; NAB1; LITAF; HES1; ESR1; TCEA1; NELFB; CNBP; USP21; ZNF281; YWHAB; ZBED1; SMARCA1; RAD21; RBM39; TAF7; ZNF410; HDGF; UBE2B; INSR; FOXO1; RBFOX2; PTTG1; TRPS1; ID1; SSRP1; PHF20; RNF4; BASP1; KLF9; LPIN2; TFDP2; ABL1; PAX5; TLE2; VEZF1; SSBP2; ZNF672; RBBP5; ARID5B; ID3; BANP; SCAND1; TCEB2; SERTAD2; RBL2; TOB1; ADNP; TSC22D2; ATF1; BBX; RFX5; TFAP2A; CEBPA; PSIP1; KAT6B; LOXL2; UBE2I; CENPF; TDP2; HIRA; SPIB; TBL1X; JUNB; FOXN3; ID2; TXNIP; ZBTB38; SMAD1; CARHSP1; SMARCD3; BCL11A; RUNX1; ZIC1; PBX1; PAWR; TWIST1; THAP11; KLF10; XBP1; PAX6; MYBL1; ZNF91