Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID22187	Osimertinib	GSE70138	ASC	Human	24h	0.12uM	EID0026

Response Information :

Types	Number	Response transcription factors
Up-regulation	82	ZNF131; CREG1; HMG20B; MED24; RHOA; POU4F1; PMF1; GATA3; MYT1L; SMARCC2; ZNF107; SUV39H1; ZNF23; NR2E1; NFIC; YEATS4; POU2F1; TERF2; PAX5; POLR3F; EN2; RORA; ARID1A; ZNF146; ZNF85; MBD4; IKBKAP; CNOT2; PGR; PBXIP1; AR; ZMYND8; SMAD5; ING2; MEOX2; BCL3; MLXIP; YBX3; KDM5D; CITED1; TBX21; ZNF302; ZNF580; NR0B1; MSX1; CUX1; HOXA11; TRIP6; TBX3; SOX13; IFI16; BHLHE40; INSM1; REPIN1; HHEX; SAP30; PCGF2; SMARCA2; APEX1; TAF7; SMAD3; RBPMS; SREBF1; CBX5; SIX3; TCERG1; FOXG1; SIX1; JUNB; TRIM16; MXI1; HLF; MNDA; PBX1; ZNF91; BASP1; XBP1; BCL11A; EMX2; CD3D; HOXC10; MYBL1
Down-regulation	57	USP22; NPAT; AEBP1; NAB1; AHR; BRD7; PHF1; MXD1; PBX3; HNRNPD; CCNH; AFF1; RBBP8; ELF1; ATF1; HMGB3; DNAJC1; NR4A2; IRX4; NR4A1; ARNT2; TOB1; ZFP36L1; ZNF189; ID1; BCL10; RNF111; SNAI2; E2F3; ISL1; VDR; CREBL2; ZNF165; ASCL1; HOXD1; CREB3; CARHSP1; RB1; HOXC6; ZNF217; IRF7; DACH1; TDP2; BRD2; TFAP2A; ZFPM2; LEF1; TCF21; TFDP1; NKX2-1; MAF; TSC22D2; TOX3; DAXX; HMGN3; MAFB; ID4