Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22153 Gsk-1059615 GSE70138 ASC Human 24h 10uM EID0026
Types Number Response transcription factors
Up-regulation 46 FOXO4; TCEA2; CEBPZ; RELB; TCF15; APBB1; HBP1; CEBPA; TCF25; HMGA1; HDAC6; SETD2; NR3C2; BCL3; HDAC5; HOXA5; CBFA2T2; PBXIP1; ELF2; STAT6; HDAC4; TSC22D1; FOSB; CBX7; PHF20; MEOX2; KLF11; PATZ1; TLE2; HOXD1; ARID5B; BAZ2B; ARID4B; MAFF; KLF5; KAT6B; RBPMS; RBPJ; FOXN3; RUNX3; SPIB; PBX1; AHR; ZHX2; ELK3; ATF3
Down-regulation 31 ZNF274; JUN; RUVBL1; ENO1; CDYL; ZNF430; WT1; RAN; MYCBP; HSBP1; TRIM32; RNF14; AEBP1; PEG3; PSMC3; HMGB1; PRRX1; ASCL1; NPM1; TCF21; RREB1; LEF1; ID2; SNAI2; SIAH2; NR2F1; EGR3; TFEC; XBP1; DACH1; HOXC10