Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22145 Doramapimod GSE70138 ASC Human 24h 0.12uM EID0026
Types Number Response transcription factors
Up-regulation 35 E2F2; IKBKAP; ZNF532; YBX1; SMAD5; BRCA1; TAF9B; SOX12; CALR; PTRF; BCLAF1; EHF; DDX5; TGFB1; KAT6B; RFX5; TGFB1I1; WWTR1; MBD2; PTTG1; RBPMS; HOXC6; HHEX; ZBED2; ZBTB18; HOXC10; DACH1; PITX1; XBP1; SMARCA1; IFI16; ELK3; INSM1; MSX1; THAP11
Down-regulation 39 BRF2; ZNF136; NFATC4; ZMYM2; CCNH; CRYM; IRF9; ZNF512B; BNC2; ZNF273; TFAP2C; IRF7; ZNF264; REL; TCF7; NCOA1; HTATIP2; TLE4; TWIST1; GRHL2; AHR; FOXO1; LITAF; RBPJ; NCOA2; TOX; FOXA1; HOXB2; HIVEP1; BCL6; MYRF; ZNF117; SMAD1; SP140L; ARNT2; ZNF91; MYBL1; DAXX; BASP1