Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22134 Ibrutinib GSE70138 ASC Human 24h 0.04uM EID0026
Types Number Response transcription factors
Up-regulation 33 FOS; OLIG2; CBFA2T2; PRDM2; ZMYND8; ZNF85; SOX13; SSX1; TFAP2C; NANOG; RORA; FOXG1; SOX17; ZNF331; FOSB; CITED1; HIPK2; KLF11; ID4; TWIST1; NR4A2; SMAD1; PBX3; TRIM24; APEX1; ISL1; ZNF117; LOXL2; TOX; HEY1; ARNT2; MEIS2; BHLHE41
Down-regulation 27 TCEB2; TBL1XR1; RREB1; ZNF148; ZIC1; STAT6; ZNF146; RCOR1; RNF10; ASCL1; REL; PITX1; WWTR1; ZNF532; SMAD2; DNMT3B; IRF1; ETS2; PLAGL1; HLTF; CTR9; BTG1; TRIM22; MECOM; SMARCA1; NR1D2; MAFB