Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22130 Ibrutinib GSE70138 ASC Human 24h 3.33uM EID0026
Types Number Response transcription factors
Up-regulation 43 ZNF589; NAB2; TCF3; HOXD1; TCF7L1; GATA6; PBX3; NR5A2; FOXK2; HMBOX1; E2F8; SOX10; STAT4; CENPF; E2F3; HEY2; ZHX2; ATF3; MEIS2; ZNF423; ZNF536; SOX11; ERBB4; HDAC9; NANOG; TSC22D1; ZNF232; FOXC1; MYBL1; SATB1; CTBP2; TFAP2C; PBX1; TFEC; ZEB1; TOX; ARNT2; OSR2; TRIP6; SOX9; TRIB3; ZFPM2; MYRF
Down-regulation 36 ZMYM2; CEBPD; NFE2L2; ASCL1; NCOR2; MAFB; TOX3; ESR1; CTNNB1; ZBTB1; AES; NCOA1; KLF9; AEBP1; KDM5D; SMAD2; ZBTB38; RORA; SIAH2; LEF1; DLX5; PIR; HOXC6; MED1; TSC22D2; CERS6; IRF2; MSX1; TCERG1; DACH1; NR1D2; SUB1; TBL1X; HOXC10; SMARCA1; SATB2