Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID22070	Mitoxantrone	GSE70138	ASC	Human	24h	10uM	EID0026

Response Information :

Types	Number	Response transcription factors
Up-regulation	145	ARL2BP; RING1; HOXC5; NFIX; IKBKAP; NAB2; PHOX2B; ZNF586; HMGXB3; GTF3A; ZNF528; PHF1; SETD3; SUPT4H1; DAXX; ZNF556; CERS6; WNT4; HIVEP3; HDAC1; HNF4A; SHOX; SSBP3; FOXD1; HDAC11; HOXC8; WDR77; SHOX2; TCFL5; KLF12; NHLH1; NR1I3; RARG; TAF11; PAX1; ZNF551; TCF7; ZNF671; SOX21; NKX2-1; NR1I2; TWIST1; DLX4; AEBP1; SOX2; GBX1; POU4F2; ZNF134; ONECUT2; ZNF415; ZNF552; NEUROG1; RBBP8; SRF; NR0B2; LHX3; CNBP; TAF9B; TFDP2; ZNF606; SREBF2; ZNF304; FUBP1; NHLH2; MXD4; ZNF587; FOXF1; HOXC4; TBX2; WWP1; CREBL2; TLX2; ZMYND11; ENY2; WWTR1; ZNF124; ACTL6A; PEX2; SAP18; PRRX1; SNAI1; TCEA1; CDK2; SMAD2; SIM1; CDIP1; TCEB2; ASH2L; ZNF419; HDAC3; CBFB; PIAS2; ZNF711; NANOG; ATF1; SMARCA1; NR4A1; ACTL6B; TFDP1; GATA3; ZNF211; PBX3; NOC2L; DDX5; INSR; SATB1; MYT1; KLF7; NFE2L3; ERBB4; HOXD3; SATB2; NR4A2; SUB1; SIX3; NR5A2; RNF14; TGFB1I1; TDP2; NR3C2; ZNF264; VDR; ZNF721; TGFB1; DLX2; ZNF544; CD3D; NR2F1; HMGB1; LOXL2; PITX1; TRPS1; HLTF; HMGN3; ST18; HOXC6; ID4; ZNF423; ID1; ZBED2; MEIS2; HOXC10; DACH1; ZNF91; PEG3
Down-regulation	156	NRIP1; TLE1; NFIL3; CEBPD; CDK7; FHL2; CEBPB; MYC; FOXO3; TSC22D3; TAF9; NFKBIA; PDLIM1; XBP1; PHF20; CEBPZ; KAT6A; TBPL1; RYBP; JUN; ZNF146; SPEN; PLAGL2; CEBPA; ZNF22; NCOA3; RNF111; SAP30; ZNF12; RLF; ZNF267; SCAND1; FOXJ3; PNRC1; CCNA2; DDIT3; SETDB1; NUP62; PATZ1; USP21; MTF2; ARID5B; ZNF7; KLF9; SERTAD2; TMF1; YBX3; MNT; ZFP36L2; KMT2A; NRBF2; NPAT; ID2; PIAS1; TAF5; NCOR1; SMAD3; ZZZ3; BCL10; ZNF217; CDYL; RORA; BCOR; ZFP36L1; ZNF148; TSC22D1; ARNTL; ZNF292; THAP10; ASXL1; PUF60; AATF; BRD4; ELF2; NFE2; HES1; SOX17; SMARCA2; ARID5A; ASCL1; ZMIZ1; TLE4; HBP1; ATF4; AGO2; ZBTB7A; MED6; ZBTB11; PQBP1; ARID4B; HMGXB4; ZBTB16; ELF1; KAT8; PITX2; BAZ1A; TERF2; ADNP; BTG1; CRK; HIVEP2; CTR9; ZNF24; CHD7; MAGED1; CEBPG; BCL6; MAX; ZBTB1; DDX17; ZNF232; ING3; TGIF1; SREBF1; MAFB; RBM39; BRD8; NCOA2; PBX1; NKX3-1; NR1H3; ZHX2; ZEB2; CDK8; CTBP2; FOXO1; TBP; JUNB; ELF5; TCF4; IRF2; RAN; TRIP6; RUNX3; SMAD1; CHD8; SIAH2; MXI1; BASP1; SNAI2; VPS72; POU2AF1; SALL1; MYRF; NR2F2; ERG; TOB1; EGR2; CITED2; SMARCD2; FOXG1; KDM5A; SMAD7; MEIS1; SUV39H1; BHLHE41