Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22025 Osimertinib GSE70138 ASC Human 24h 0.37uM EID0025
Types Number Response transcription factors
Up-regulation 14 GATA3; NR1H2; DNAJC1; ELF5; TRPS1; MEIS2; KLF6; ATF3; ZNF512B; MECOM; MAFB; WT1; TFAP2C; ESR1
Down-regulation 20 ID1; ING2; RNF138; KLF10; NR3C2; FOXO1; ID2; ZBTB38; ZBTB16; PSIP1; ING3; JARID2; HOXC6; TXNIP; NR2F2; ELK3; KLF4; CITED2; MAGED1; CREB1