Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21714	Mitoxantrone	GSE70138	SKL.C	Human	24h	10uM	EID0066

Response Information :

Types	Number	Response transcription factors
Up-regulation	122	NFATC4; KAT6A; MAK; FOXJ1; TBX2; SSX7; POLR3C; MAML3; PHOX2B; ZNF835; NEUROD1; WDR77; TGIF2; EPAS1; HOXC5; PRRX1; MYCL; INSR; PROP1; BNC1; PRDM14; RBL1; GCFC2; BNC2; SOX18; CNBP; TFCP2L1; ASH1L; TLX2; HIPK1; NR1I2; MYBL2; HNF4A; NR1I3; DCC; TRIP4; PAWR; MECP2; TSC22D2; VGLL1; TCEA1; ZNF75D; TEAD3; TDRD3; NHLH1; ZNF423; ZNF665; MYRF; NANOG; SCAND1; ZNF606; ZNF528; ZSCAN18; HOXC4; PGR; KLF7; FOXA2; NCOA6; IRF6; NR5A2; ZNF8; TTF2; ESR1; HOXD3; POU2AF1; HIPK2; MEOX2; FOXI1; CDIP1; DLX2; PAX6; NR0B2; ELF1; ZMIZ2; GLI2; MEIS1; CBFB; NFX1; POU4F2; ZNF573; BRIP1; FOXN3; ZNF264; ZNF589; NR2E1; ZIC3; LIN28A; MTA1; PDLIM1; CDK2; LHX6; PSIP1; GTF3A; SOX17; VPS72; RAD21; MECOM; SPIB; CTNNB1; EYA2; YBX1; ATF1; EED; PSMC3; MYCN; TWIST1; GATA6; PTRF; ZBED2; TFEC; MNDA; LITAF; CALR; BAZ1A; MAFB; TP53; CEBPD; ELF3; WT1; ZFP36L1; ZNF652; ARNT2
Down-regulation	105	NFKBIA; CDK7; FOSL1; TBP; TBPL1; MEF2C; JUN; HMGA2; NFIL3; MYC; CHD7; BHLHE40; NUP62; SMARCD2; ITGB3BP; ZBTB11; HMG20B; FOXJ3; EGR1; CCNE1; BRD8; HOXA5; HOXA10; SIX2; NR4A2; MED21; MNT; BASP1; CIZ1; RREB1; THAP11; KAT8; SOX4; FOSL2; HOXA7; EGR3; KAT2A; SSX1; TGIF1; DEAF1; PATZ1; BANP; SP140L; MED24; SIX1; ZBTB16; ADNP; PAXBP1; TCEA2; HMGXB4; ZNF232; MED6; MAX; MKL2; SATB2; NAB1; KLF2; PITX1; URI1; GABPA; BTG1; CEBPG; TSC22D1; NR4A3; TBL1XR1; SP100; JUNB; YBX3; SREBF1; NR4A1; CITED1; SMARCD3; MED1; ZNF302; ZNF430; PIR; ZNF331; PCGF2; HOXB6; TULP4; ZNF587; TAF1D; RXRA; VGLL4; IKBKAP; APEX1; ZIC1; NKX3-1; KDM5D; HOXB2; KLF9; HOXC10; MXI1; RUNX1; HEY1; ETS2; TOX; EGR2; CRK; MTF2; TOX3; CITED2; TRIM22; ID1; NR3C1