Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21696 Idelalisib GSE70138 SKL.C Human 24h 3.33uM EID0066
Types Number Response transcription factors
Up-regulation 57 ZNF175; MEF2C; NFATC3; SFPQ; ZEB2; HIPK3; PA2G4; FLI1; DDX17; PURA; MBD2; TLE2; PTTG1; PPARGC1A; MAFB; AHR; KLF4; HOXC10; KLF9; ZNF573; CREBL2; HOXA1; KLF5; DACH1; SAP18; IRF6; NCOA6; NFAT5; CTBP1; TGFB1; SSBP2; ERBB4; FOXM1; NR4A1; AES; MYCL; PTRF; ING3; CNOT3; TWIST1; PBX3; KDM5A; MAF; TCF4; CALR; IRX5; FOSL2; CDK2; BHLHE41; TP63; TRIM29; LMCD1; ID4; HEY1; AEBP1; TBX3; TSC22D1
Down-regulation 82 SP140L; STAT3; ZNF268; ZNF232; RORA; MYRF; COPS2; THAP11; BATF3; ZNF195; ARNT2; TCF21; ZNF3; BMI1; MLXIP; MDM2; MZF1; ZNF239; ZNF32; NFE2; PHIP; PQBP1; ZNF354A; KLF1; SETDB1; ETV5; ZNF14; CUX1; SALL1; SP100; IRF9; ZNF423; ASCL1; ILF2; ZNF415; PIAS1; HMGA1; ZNF711; NPAS2; HHEX; OLIG2; ANKRD1; YEATS2; CRY1; ID2; ZNF43; TRIM24; ZNF107; ZNF652; ZNF512B; GATA4; MAGED1; TAL1; ZNF131; MED13; ZFP36L2; SOX11; ZSCAN18; MNDA; ZNF430; ZNF91; LITAF; VPS72; BACH2; STAT4; LEF1; ID1; CEBPD; HMGB2; SMAD1; ZHX2; HMGN3; POU2AF1; NKX3-1; ZEB1; MYB; WT1; TRPS1; MEIS2; PEG3; PIR; ZNF586