Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21684 Bms-509744 GSE70138 SKL.C Human 24h 3.33uM EID0066
Types Number Response transcription factors
Up-regulation 91 HES1; KAT6A; EED; NHLH2; ZNF536; FOXF2; CBFA2T3; EPAS1; HOXB2; PAX6; TFAP2A; INSM1; HOXB5; HR; NR2F6; NHLH1; NR1I2; MBD4; ADRB2; BCL11A; SOX3; NEUROD1; ACTL6B; SP140; SKIL; ZIC3; PRRX2; MYRF; RSF1; ZNF532; CREB5; ZNF529; CREBZF; TRIM16; SOX11; TFEC; HOXB6; ZNF573; EN1; CEBPD; LITAF; ZNF611; ZNF329; TCEA2; ZNF423; ARNT2; ZNF264; HDAC9; MED23; EHF; FOXF1; ZEB1; SOHLH2; ID1; GATAD2A; VPS72; TRRAP; NKX2-2; SPDEF; HMGA1; NPAS2; BHLHE41; SOX9; HOXD1; ZNF160; IFI16; EMX2; CTBP2; ST18; HEY1; IRF6; KLF5; ZNF331; JUP; ZBED2; HTATIP2; ZNF721; NR4A2; SSBP2; IRF7; TRIM29; KLF4; PITX1; ZNF83; RUNX3; MYBL1; ID4; AHR; TOX3; ELF3; ZIC1
Down-regulation 70 CREB1; NFYC; LZTS1; ZMIZ2; ZNF593; RXRA; MAGED1; LEF1; BATF3; RORA; HDAC1; ELF1; BLM; FLI1; ZEB2; VGLL4; JARID2; MEF2A; EGR1; ING3; NCOA1; NFE2L1; MED21; RNF6; HOXA10; MSX1; MLXIP; RNF14; RFX5; ZNF516; PATZ1; FOSL2; HEY2; EDF1; ZNF267; FOXL2; ZMYND8; MSC; EGR3; SMARCA1; RLF; PQBP1; ZNF410; KLF10; PEG3; PSIP1; FLNA; ZBTB1; ARNTL2; KDM5D; IKBKAP; NR2F2; TOB1; TBL1X; RBBP8; PIR; MAFB; ZBTB16; MED1; TBX3; HMGN3; REPIN1; ZFP36L1; FOXO1; SMAD1; WT1; TRPS1; BTG1; NRIP1; E2F2