Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21681 Pd-0325901 GSE70138 SKL.C Human 24h 0.12uM EID0066
Types Number Response transcription factors
Up-regulation 107 FOS; MYBL1; ERBB4; PBXIP1; BRD4; CBFA2T3; COPS5; MYRF; TOX4; MYBL2; POLR3C; RB1; ELF4; ID4; ZNF232; SMAD1; NFIL3; CUX1; VPS72; ZNF467; CHD7; ASH2L; HOXB2; NFIC; HEY1; SMARCC2; PEG3; KLF7; SUMO1; CREB3; CEBPG; PRKDC; MYCL; JUND; EMX2; PAX6; ZSCAN31; HLX; SALL2; NEUROD1; IRF9; TCEA1; ZHX2; MXI1; TRIB3; AIP; AHR; PRPF6; SOX17; ZFP36L2; KLF10; SIX3; ZNF415; GLI2; MYCN; BAZ1A; TCF4; FOSL2; STAT6; HIRA; CEBPD; KLF4; KLF13; KLF6; ZNF140; ILF2; ZFPM2; HEY2; FOXO3; CRYM; GATA6; TSC22D2; NCOA1; ATF3; SOX11; INSR; NFE2; TCF7; PSMC3; HMGB3; NANOG; MEIS1; ZNF264; RUNX3; SSBP2; BIRC2; SP3; E2F5; TOX; CTBP2; APEX1; WT1; ID1; ASCL1; FOXO1; ARNT2; VGLL4; ZNF131; BACH2; CALR; PDLIM1; FOXG1; IRF8; HHEX; MECOM; ZIC1; TRPS1
Down-regulation 74 HMGA2; FOSL1; EGR1; CDYL; STAT3; FHL2; ABL1; UBE2I; EDF1; PTTG1; CDK8; RNF4; ETV1; TTF1; TRIM32; BLM; ALX1; MAGED1; NR1H3; ZMYM2; NUP62; NELFB; MLX; NR1H2; HSF2; EGR3; LIMD1; TEAD1; SAP18; ETV4; CTR9; NR4A1; RFC1; TGFB1I1; NRBF2; CCNA2; RCOR3; MED24; DLX2; CBX3; PSPC1; BRD8; TCEB2; FOXL2; EED; ZMYND8; SATB2; BMI1; NR2F1; HOXA10; CARHSP1; ISL1; IRX5; GTF3A; TRIM24; NFE2L3; CITED2; HOXC10; BASP1; KLF5; FOXA2; IKBKAP; RBPMS; NKX2-1; LITAF; MYC; IRF4; JUP; NR4A2; ELK3; NR1D2; SUV39H1; NRIP1; SOX9