Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21673	Osimertinib	GSE70138	SKL.C	Human	24h	1.11uM	EID0066

Response Information :

Types	Number	Response transcription factors
Up-regulation	77	FOS; NR4A2; TBX2; CSDE1; ZNF202; ZFP36L2; PNRC1; ZNF165; NCOA2; PURA; KMT2A; JUND; CAMTA1; NR4A1; NR4A3; TCF21; TDP2; MEIS1; MAF; UBE2B; RBM39; GATA6; SNAI2; SIX3; TLE4; INSM1; ZNF331; CREM; HOXB13; ID4; SOX10; ELF1; KLF4; RYBP; ERBB4; SPDEF; BCL11A; AEBP1; FOXN3; STAT1; PBX3; NKX2-2; IRX5; MTA1; DNMT3B; BCL6; HOXC6; NCOA1; HOXC4; NPAT; KLF9; ETS1; RUNX1; HIRA; CARHSP1; IRF9; DACH1; KLF5; MSX1; RBBP8; PBX1; NKX3-1; ARNT2; NRIP1; ZNF83; PAX6; CDK2; TRIM29; ATF3; NR2F1; OSR2; IRF7; IRF6; PIR; FOSB; TFAP2C; SOX9
Down-regulation	64	HMGA2; FOSL1; RORA; ELK3; EGR1; PCGF2; NFIC; TAF1A; POU2AF1; ZNF45; PSPC1; MED24; CREB3L2; ZNF593; NR1H3; REST; KAT2B; MEOX1; RBPMS; ZEB1; NR3C2; VGLL4; NFIB; CTR9; RUVBL2; SAP30; ZNF12; ZNF148; PLAGL1; ZNF177; NCOA4; ARNTL2; ZNF217; IRF4; TCF7L2; MYCN; PTRF; ZBED2; ZBTB18; TGFB1I1; ZNF430; WWTR1; BCL3; ZNF131; CD3D; HMGB2; SMARCA1; MAGED1; SP3; SMAD1; KLF2; HMGB1; MYT1L; HHEX; ZSCAN18; SOX11; BAZ1A; CALR; HLF; CEBPZ; PUF60; LEF1; HOXB7; E2F2