Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21671	Osimertinib	GSE70138	SKL.C	Human	24h	10uM	EID0066

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	FOS; ETV1; NCOA3; RORA; NFIL3; SATB1; ZNF324; NFKBIA; ARID3A; THRB; LDB1; CSDC2; ZNF331; TSC22D3; TFAP2A; JUND; ZNF415; PEG3; ING4; HMGA1; TDP2; NR2C1; KLF6; SUPT3H; CDC5L; HMBOX1; SOX5; PROX1; EN1; ACTL6B; SREBF1; INSR; PLAGL2; PEX2; ERBB4; ETS1; ZNF10; NR0B2; NR5A2; ARID5B; MED20; CEBPD; TCF7; THAP10; MAFG; MDM2; ELF5; ELK3; PGR; RSF1; ZNF165; ARNTL; ZNF304; ASXL1; SIX2; PBX3; GRHL2; VGLL1; ZNF665; FOXF2; TRPS1; OVOL2; SIX3; NR2F6; JUNB; TFAP2C; BRD4; HDAC9; ZNF266; ATF3; RBBP8; HBP1; STAT4; FOXA1; ZNF516; KLF11; NCOA2; OSR2; FOXC1; ZNF117; WT1; SMARCA1; ZFPM2; SOX9; PDLIM1; SP100; TBX3; AFF1; HHEX; ZNF410; MSX1; HEY1; FOXA2; ZFP36L2; INSM1; PBX1; CREM; BRD2; NR2F1; SNAI2; ZNF83; PITX1; ASCL1; VGLL4; ZBED2; TRIM22; FOSB; TOX3; TOB1; IRF6; TSC22D1; ZNF131
Down-regulation	71	FHL2; CREB1; PARP1; ECD; HDAC2; EZH2; UBE2L3; SUZ12; RUVBL1; ZEB2; PSMD9; ASH2L; TCF3; EED; PTTG1; CCNA2; LOXL2; PITX2; EGR1; MAGED1; POU2AF1; RRN3; HMG20B; DLX2; ITGB3BP; MAFB; BHLHE41; HOXA10; EGR3; TAF10; ID3; FOXD1; BCOR; TAL1; TRIP6; YEATS2; C1QBP; FOXJ3; TCEB2; HSBP1; EDF1; NCOA1; TLE4; HOXC6; YWHAB; TSC22D2; NAB1; CBX3; PSIP1; ZNF22; RLF; BCL11B; MED1; HOXB7; AEBP1; EGR2; GLI2; NCOR2; PTRF; PSMC3; IRF4; CALR; LEF1; NKX2-1; ETS2; ZBTB18; KDM5D; HMGN3; CEBPZ; RUNX1; TRIM29