Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21657 Wz-4002 GSE70138 SKL.C Human 24h 0.12uM EID0066
Types Number Response transcription factors
Up-regulation 81 FOS; DMTF1; TERF2; NR1I2; TAF4; DEK; RB1; KLF2; TFAP2A; KDM5A; ZNF268; BCL11A; NFATC1; KLF9; GFI1; PROX1; TDP2; HLX; NFE2; TAF5; TXNIP; SOX10; KDM5C; CREBL2; CREB3L2; MDM2; PBXIP1; ID4; MXI1; MYB; PRRX1; TGIF1; SMAD6; ZBTB38; RBL2; HDGF; AES; INSR; ZFP36L2; ARID5B; CDK2; ISL1; TFDP2; ETV5; THAP10; VDR; TGFB1; RBPJ; KLF11; TCF7L2; GTF3A; SUB1; JUNB; ARNT2; AEBP1; ATF3; CBFB; ZNF107; ATF1; LMCD1; PHIP; NR2F1; HMGB1; IRF6; BBX; GLI2; DACH1; BACH2; NFIB; VGLL4; TBX3; NFAT5; EMX2; ST18; ZNF423; NFE2L3; RUNX1; PAX5; KDM5D; TRIM22; ELF3
Down-regulation 66 RNF4; ZNF593; CDYL; BASP1; TTF1; KAT7; TAF12; PSMC3IP; EED; MED17; NELFB; HOXC10; EDF1; TBL1X; KLF10; FOXA1; ZNF3; GATAD2A; PEX2; AR; PMF1; RERE; ZBTB43; RFC1; ADNP2; TRIM32; SIX2; DNMT3B; SMARCA1; PIAS2; KAT6B; NEDD8; TOX3; TAF1D; IRX5; ENO1; FOXL2; NR2F2; PDLIM1; AHR; SIX1; ERG; NR4A2; SMAD2; KLF6; MSX1; CCNA2; RUNX3; TRIP6; PAWR; NKX2-2; LPIN2; ATF4; TRIM16; SMARCD3; BMI1; BHLHE41; FOXF1; HOXB6; LITAF; HOXC6; ZIC1; HOXB7; NRIP1; LEF1; E2F2