Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21630 Doramapimod GSE70138 SKL.C Human 24h 10uM EID0066
Types Number Response transcription factors
Up-regulation 93 ZMYM2; IKZF1; PSPC1; ADRB2; GATA3; ZNF654; MGA; HDAC9; ERG; ZSCAN16; ZBTB44; MTF2; EZH1; ZMYND11; CAMTA1; URI1; RAN; TAF12; ZBED1; PHOX2B; SMARCA1; ZNF281; RFC1; HMGA1; RORA; ZNF165; ZNF7; ZNF12; BRD3; CBX6; TWIST1; TGFB1; GTF3A; ZBTB20; CUX2; FOXD1; ZNF32; NR1H3; DR1; SOX10; SAP18; TCF7L2; PRKDC; DEAF1; HBP1; CREBL2; MLLT10; JAK2; ZNF337; ISL1; ELK3; SHOX2; BCOR; CBX7; NR3C2; MAFF; TCF7; LPIN2; HHEX; CEBPG; EDF1; ZBTB16; HLF; RUNX3; TLE2; KLF11; PHIP; TRIP6; TAF1D; ATF4; WWP1; SMAD1; MED1; FOXO1; BBX; MYBL1; ZNF160; NR4A2; BACH2; CTBP2; BHLHE41; MYT1L; DACH1; ZBTB38; ZNF721; RBPMS; NRIP1; KDM5D; AHR; ATF3; ARNT2; IFI16; HOXB7
Down-regulation 58 ZNF205; HDAC7; TCF15; ZNF646; POU3F2; HOXB3; ZNF444; ZNF787; CNOT1; MEF2D; EVX1; ZNF219; HMX1; HR; TDP2; HOXC10; HMGB3; POLR2A; ZNF768; DPF2; HIVEP2; MDFI; WT1; TRIM16; GATA6; ATF2; KLF5; SMAD6; TCF12; ID2; TCF21; MAX; TRIM24; MYRF; FOXF2; EMX2; MNDA; CTNNB1; RBBP8; HMGN3; TLE4; ASCL1; IKBKAP; ZHX2; MEIS1; VDR; KLF4; TCF4; TOX3; REPIN1; CEBPD; OSR2; JUP; MYB; MEIS2; PDLIM1; E2F2; ZNF586