Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21618	Ibrutinib	GSE70138	SKL.C	Human	24h	10uM	EID0066

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	MED7; MYNN; DNMT3B; NFIL3; ZNF175; NR3C1; HOXA5; GATA2; HOXA7; HMGXB4; ARRB1; NAB2; ZNF432; HOXC6; DLX4; FOXO3; TCF20; CRYM; ZNF8; ZNF33B; SUPT3H; PMS1; NR1H4; NR1H3; HOXC4; YEATS4; ZNF133; SOHLH2; CREG1; HOXB2; XRCC6; GATA6; GCFC2; OSR2; ZNF267; NR2F6; MXI1; TDP2; CERS4; TBX21; HIC2; ZNF200; HOXB6; EP300; BCL3; NFKBIA; HOXB13; ZNF468; PURA; KLF7; CBX7; FOSL2; TCEA2; CUX1; SPDEF; ZNF266; ZNF239; NANOG; TCF7L2; SMAD1; BCL6; NR1H2; AHR; TEAD4; SNAI2; TAF10; HOXB7; PITX2; HOXB5; ERG; DACH1; PDLIM1; SAP18; VPS72; MED21; IRF7; HOXC10; HLX; LMCD1; CEBPD; LPIN2; KLF2; KLF5; ELF3; APEX1; MSX1; ZNF423; TRIM22; NFIB; ATF5; HEY1; IRF8; TSC22D1; ATF3; WT1; MECOM; IFI16; PIR; MAF; ZBTB18
Down-regulation	71	HMGA2; FOSL1; EGR1; TGFB1I1; FHL2; RBM14; ETV1; BAZ2A; TCF7L1; POU2AF1; SFPQ; SMARCC2; YAP1; EED; PTTG1; HSF1; HOXA10; CHD7; MBD2; SP140L; FOXM1; INSM1; BAZ1B; PTRF; TADA3; LHX2; GTF2I; NFX1; KMT2A; TCF12; AEBP1; ID2; ZBED2; COPS2; MDM4; CCNA2; NPAS2; GTF2IRD1; TRIM16; LEF1; ZBTB38; ZMIZ2; TFEB; ZSCAN18; PAX5; NKX2-1; CRY1; KDM5D; PSIP1; ZNF410; FOXG1; TLE4; KLF6; REPIN1; TRIM29; HMGB2; ZHX2; HMGA1; SMAD7; SATB2; HHEX; ZNF512B; IKBKAP; ZBTB16; BMI1; IRF4; NR1D2; GLI2; NRIP1; TFAP2C; TXNIP