Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21613 Kin001-244 GSE70138 SKL.C Human 24h 3.33uM EID0066
Types Number Response transcription factors
Up-regulation 213 ZNF74; ZNF362; ZNF654; DNMT1; ZNF507; ZNF217; ZNF623; MAK; ZNF345; HOXB2; HIC2; SOX12; ZNF81; TERF2; ZNF214; GMNN; ZNF780B; SUV39H2; ZNF234; ZNF112; THAP9; FEZF2; ZNF749; CARF; HOXB5; NEUROD1; ZNF223; NHLH2; ZNF225; IKZF2; ZBTB44; NR2F1; MYNN; SOHLH2; ZNF471; ZNF80; PAX4; ZIC3; GCM2; ZKSCAN4; ZNF492; ZNF407; TAF1A; ZBTB3; ZNF835; ZNF391; CHD2; GATA2; THRB; SALL2; BLZF1; SOX30; DCC; ZNF157; NACA2; ZNF674; ZNF695; PGR; ZNF177; ZFX; ZNF239; NFE2; ZFP2; ZNF573; ZSCAN9; L3MBTL1; ZNF334; ZNF613; ZNF180; VHL; ZNF415; NFATC4; BCL11A; ZSCAN12; EHF; HDAC9; ZNF816; PHOX2B; HOXB6; ING2; ZNF287; ELF4; ZFY; ZNF304; WT1; E2F8; ZNF493; ZNF281; ZNF813; POU2F3; PLAGL1; YEATS4; ZNF141; SCAI; NR5A2; MXI1; SKIL; NFIX; ZKSCAN7; ISL1; CERS4; PLAG1; ZNF117; ZSCAN16; ZFP30; NKX2-2; ZNF350; ZNF506; ID1; HEY2; ZNF257; ZNF45; ZNF529; NR1H4; ZNF669; SMARCA1; DAXX; ZNF580; ZNF195; SP140; TAF10; POU4F2; CBX5; AHR; TTF2; EYA2; WNT4; HNF4G; E2F3; NR0B1; HMGA1; TFEC; TAL1; MAFF; CDK8; MEOX1; ZKSCAN1; MEIS1; ZNF557; FOXE1; EED; VGLL1; MYBL1; NANOG; ZNF83; TCF25; ZNF426; HAND1; CBFA2T3; INSM1; ZNF467; STAT6; SSX1; LIN28A; CDK2; ESRRG; ZNF667; MYCL; FOXL2; AR; TLE2; SOX17; ARNT2; ZNF107; INSR; TWIST1; SIM2; KLF4; SOX11; EP300; TFAP2C; SIM1; ZBTB18; GATA4; ZNF211; ZNF516; MYCN; DNMT3B; JARID2; HLX; LITAF; EGR2; ZEB1; WWP1; PBX1; ERBB4; NR3C2; NKX3-1; PAX5; MYB; TGFB1; IFI16; NCOA4; TP63; TOX; HLF; RUNX3; ELK3; HHEX; MEIS2; ELF3; TSC22D1; CITED2; PDLIM1; HEY1; TBX3; KDM5D; ATF3; ZBED2; PBX3; HOXB7; TOX3; ZIC1
Down-regulation 43 TSC22D3; STAT1; NUP62; DNAJC1; SREBF1; ID2; BAZ2B; MXD4; IRF5; PREB; KMT2A; BBX; SIX1; TCF12; CRY1; FLNA; IRX5; MKL2; NFKB1; ZNF331; ZBTB38; PTRF; TBL1X; IKBKAP; ZHX2; PIR; BIRC2; PSIP1; CD3D; SOX9; NR4A1; POU2AF1; AEBP1; MAFB; BMI1; NFIB; NR1D2; TRIM29; HMGN3; NRIP1; RUNX1; MTF2; E2F2