Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21598 Gdc-0068 GSE70138 SKL.C Human 24h 0.12uM EID0066
Types Number Response transcription factors
Up-regulation 96 FOXO4; PTTG1; NAB2; TMF1; MLXIP; RNF4; ZNF787; ZNF205; UBTF; HMGB3; GLI2; MXD4; AGO2; ZNF696; UBE3A; SOX10; RAN; NEDD8; NPAT; HSF1; SKI; ZNF532; NRBF2; DR1; TOPORS; SRF; EP400; PBRM1; AATF; RYBP; MAFB; TRIM32; EGR3; ENY2; ZNF516; EGR2; CLOCK; ZNF629; MEOX1; SFPQ; AIP; MTF2; PGR; ZNF354A; MBD2; SNW1; SRCAP; BAZ2A; CBX6; E2F3; BCL10; ZNF529; WT1; SATB2; BATF; PURA; MED13; POU2AF1; ZNF84; TCF7L2; IRF4; SALL2; RUNX3; HOXA11; ZFHX4; EYA1; ID3; TCF7L1; MSC; CHD4; PAX5; LIMD1; SOX11; TAF1D; PSMC3; MED1; NR2F2; HOXC4; NR4A2; MYCN; BAZ1A; ZNF589; ZNF410; KLF10; NR2F1; PEG3; ELK3; MEIS1; DACH1; BACH2; MYT1L; ZBTB20; ZNF652; ZNF331; IRF8; NRIP1
Down-regulation 114 ZNF273; STAT1; RORA; ERG; GRHL2; CNBP; RERE; SP140L; ZNF654; PPARGC1A; NFIC; BCL11B; OVOL2; ZNF208; ZMYND8; ASH2L; TDP2; RBM39; HAND1; PRKDC; CEBPG; LIN28A; TEAD4; NANOG; MECOM; HOXB2; AR; URI1; E2F8; SMARCA5; POU2F3; ZSCAN5A; GTF3A; KLF11; ZNF263; TAL1; POU5F1B; ZNF117; IRF1; SCMH1; FOXJ3; XBP1; CTBP1; NR1H4; AFF1; CREBL2; FOXE1; RBPMS; ST18; CBX7; SIM1; IRF2; FOXN3; CBFA2T2; RNF6; TCEA1; TAF9; BCL6; TRIM22; PRRX1; ZNF304; HIPK3; BRD4; EMX2; ASXL1; ZNF552; DLX5; ANKRD1; RBBP5; ZNF419; UBE2B; TFEC; REL; ZNF430; FOXF2; TP63; BHLHE41; FOXM1; FOXG1; PHF20; SLC2A4RG; TFEB; HHEX; SHOX2; KLF2; AEBP1; TULP4; VPS72; MYB; ZNF160; ZNF266; TRIM16; AES; TP53; FOXF1; ZEB1; ZNF423; PIR; KLF5; SOX17; MYBL1; KDM5D; IRF6; HMGA1; IRF7; IFI16; TBX3; PBX1; TXNIP; ZBTB18; ADRB2; SOX9; ATF3; E2F2