Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21596 Gdc-0068 GSE70138 SKL.C Human 24h 1.11uM EID0066
Types Number Response transcription factors
Up-regulation 81 GON4L; ZNF528; E2F3; MAFB; BCL11B; MEOX1; TAF4; CAPN15; LYL1; POU3F2; CAMTA1; SOX11; C1D; ZNF467; ZNF783; EYA1; HDAC9; FLI1; HOXD1; HOXD3; BTF3; RXRG; ARNTL; DEK; TAL1; CHD3; ZNF354A; ZNF552; PHOX2B; ERG; VGLL1; MEOX2; PHOX2A; POU4F2; GLI3; RUNX3; HOXD10; TLE2; ZNF415; KAT8; NR2E1; ZNF83; TRIM32; WT1; UBE2B; ZNF32; E2F2; GATA6; GFI1; NFE2; MAFF; MED15; FOXO1; MECOM; TFEC; MEIS1; CD3D; TGFB1; SPDEF; MKL2; SOX17; TWIST1; ELK3; INSM1; ZBTB38; TCF4; NR0B1; IFI16; EGR3; ZBTB16; INSR; AEBP1; FOXG1; PEG3; FOSB; ID4; NRIP1; NFIB; MAF; PIR; TSC22D1
Down-regulation 65 STAT3; AR; CHD7; SMARCA5; ERBB2; PUF60; SP140L; PBXIP1; TERF1; ATN1; BBX; BASP1; RBBP8; PMF1; POU2AF1; CREB3L1; RBPMS; ZBTB11; MEF2A; HDAC1; RCOR3; CERS4; ZNF195; SFMBT1; POU5F1B; ELF5; RCOR1; ZNF136; MAX; RBBP5; ZBTB20; NLK; TOX3; KLF5; NR2F1; YBX3; RBBP4; FOXF2; TULP3; BTG1; PAWR; ZHX2; IRX5; SAP30; SIAH2; SUB1; RYBP; FOXF1; CARHSP1; PLAGL1; PAX5; HOXC10; TXNIP; EDF1; NANOG; MSX1; RBPJ; HLF; HOXB6; TOX; OSR2; RUNX1; KDM5D; TP63; BHLHE41