Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21593 Bosutinib GSE70138 SKL.C Human 24h 0.04uM EID0066
Types Number Response transcription factors
Up-regulation 201 FOS; HIC2; ZNF74; DNMT1; NFATC4; SOX2; GMNN; MYBL2; HIRA; BNC1; MAK; RUVBL1; ZNF507; ZKSCAN3; THAP7; TAF5L; TGIF2; VENTX; GRHL2; ZNF239; ELF4; PBXIP1; THRB; SALL2; ZNF623; TCF7L2; NHLH2; ONECUT1; TERF2; BRWD1; UBE2L3; ZBTB44; ZFHX3; ZIC3; HOXB1; CBFA2T3; TULP2; BARX1; TEAD3; ZNF273; CREB3; CALCOCO1; SOHLH2; CDK2; PIAS1; SHOX; RORC; NEUROD1; MED13; NHLH1; HDAC9; BTAF1; ZNF257; MYRF; IRX4; SIX6; ZNF467; BCL11A; IRF6; MNDA; ZNF75D; ARID3A; RNF138; ZXDC; NR2E1; ZNF232; SRCAP; PRDM14; WWC1; KLF7; SSBP3; FOXJ2; LZTR1; ARID5B; CTBP2; ZNF141; KDM4C; CNOT6; SUMO1; OVOL2; SATB1; PRDM12; CDIP1; E2F8; NR0B2; ERBB4; HOXD3; EHF; TRIB3; POU4F2; GFI1B; FOXF2; ZNF536; ZMIZ1; AR; E2F3; TFAP2C; INSR; CSDE1; ARNT2; DLX5; TFDP2; DLX4; ZBED2; CBFA2T2; ZNF133; ZNF215; ZNF337; ARRB1; PAXBP1; ZNF117; SIX3; GATA6; DLX2; TBX1; ZNF3; SOX11; ATN1; WT1; VPS72; STAT2; CERS6; ZNF562; ZNF264; MYCL; MYBL1; RSF1; ZNF354A; ZNF217; LIN28A; RBM39; GLI2; HOXB5; ATF3; HIPK1; CERS4; TRPS1; HIPK2; THRA; ZNF43; MECP2; PURA; PHOX2B; MED15; TLE2; RBPJ; NANOG; ZNF165; TCEA1; TFCP2L1; TCF7L1; THAP11; SOX9; CBX6; CEBPD; BNC2; VGLL1; HOXD1; AGO2; TULP3; JUNB; NKX3-1; LITAF; THAP10; ZNF331; HHEX; MEIS1; TRIM24; NR0B1; FOXN3; ZSCAN31; CD3D; ZFP36L2; PSMC3; ZFPM2; NFE2L3; PHF20; ZNF589; ELF3; ZNF423; CALR; CTNNB1; JUP; ZHX2; PAX6; ZNF652; INSM1; ID1; MECOM; PBX1; MEIS2; SMAD1; SOX17; ST18; RUNX1; ZNF131; EMX2; TOX3; PBX3; TRIM29; PEG3
Down-regulation 96 UBE2I; EGR3; ZNF226; HSF2; ING2; C1D; EDF1; USF2; NELFB; CCDC59; TCEB2; BRD8; WWTR1; CAPN15; ID2; EGR1; TRIM28; BASP1; IRX5; SERTAD2; RNF4; ZBTB11; NFKB1; ZNF593; HOXA10; IL16; NRBF2; GABPB1; POLR2A; ZEB2; HIVEP2; BATF; NR4A1; CARM1; TSC22D3; PIR; TAF7; ZMIZ2; RLF; STAT1; ELF1; ZMYM2; RBBP7; EGR4; MSC; IRF4; RFX5; SMARCC1; SLC2A4RG; MEF2C; ATF1; BCLAF1; BAZ2B; PSPC1; ZBTB38; YWHAB; SUB1; RORA; MED1; MED6; PRRX1; RBBP4; CRY1; MTDH; SOX10; HOXC6; MBD2; MAGED1; BMI1; DNAJC1; HMGN3; ZNF329; EED; ZMYND8; AHR; MAFB; SNAI2; CBX3; KLF10; KLF2; EGR2; PLAGL1; LEF1; NR1D2; BCL3; MSX1; SIX1; HOXC10; CITED2; NPAS2; VGLL4; TBL1X; SMARCA2; BTG1; PDLIM1; TXNIP