Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21592 Bosutinib GSE70138 SKL.C Human 24h 0.12uM EID0066
Types Number Response transcription factors
Up-regulation 53 RELB; KLF7; ZNF467; BCL3; IL16; CEBPG; CBX5; SPIB; PRRX1; ZEB1; CAPN15; ZNF552; ZNF532; NFKB1; ZNF586; ZSCAN18; HOXC4; ZNF419; NFIC; PLAGL1; PHOX2B; TRIM28; SPDEF; TCEA2; ZNF134; TP63; SMARCA1; ZNF211; SOX11; ISL1; ZNF43; SLC2A4RG; ERG; NR4A1; REL; TRIM16; HMGB3; ZBTB16; ZNF423; KLF2; ZBTB18; ZNF302; SSBP2; FOXD1; JUP; IRF4; TBL1X; HOXC6; HMBOX1; NRIP1; CEBPD; SNAI2; ID1
Down-regulation 64 TLE1; STAT1; ZNF124; MBD2; NR1H2; SOX10; WDHD1; ZMYM2; RBBP5; TMF1; UBE3A; NR1D2; HDAC4; BASP1; BRIP1; CTBP1; BAZ2A; CBX7; ETV4; ATF4; BBX; BTG1; IFI16; BRD2; TERF1; GRHL2; ETV5; ING3; IRF1; NLK; HIC2; ZNF267; CBX3; DACH1; CREB3L1; SMAD4; CHD1; SOX13; ZEB2; CRYM; KLF10; TXNIP; SMAD5; ZFP36L2; NFAT5; OSR2; TULP3; MYBL1; BHLHE41; GATA6; MED1; RBPJ; NKX3-1; SMARCA2; RUNX1; TRIM22; KDM5A; PDLIM1; PEG3; EGR2; ZIC1; LEF1; MTF2; E2F2