Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21589 Bosutinib GSE70138 SKL.C Human 24h 3.33uM EID0066
Types Number Response transcription factors
Up-regulation 141 HOXB2; GMNN; THAP7; E2F1; FEZF2; DNMT1; HIC2; TRIP11; KAT2B; HOXB1; TFAP2A; LYL1; VENTX; NFE2; E2F4; CREB3; ZNF33B; BRWD1; TLX3; RARG; MEIS1; ZNF623; SKIL; ZNF180; KLF7; TAF7L; ZKSCAN1; CSDC2; SOX18; MXI1; SSBP3; DLX5; GFI1B; VGLL1; SOX5; ZNF354A; CBFA2T2; NEUROG2; SOX17; CNOT6; ZSCAN9; MECOM; ZNF573; ARID1A; CEBPG; SRCAP; ZNF467; HOXB5; RSF1; TRIB3; KLF3; TCEA1; PRDM12; GLI3; NFIL3; PBX3; ELF4; MYCL; KLF11; ZNF24; NHLH2; PURA; KLF1; BRD7; ZNF217; TAL1; DAXX; CLOCK; EYA2; TCF21; BANP; NKX3-1; TOPORS; CTBP2; MECP2; NEUROD1; MAFG; ZNF117; LHX2; HSF1; BRD4; ZFPM2; BCL11A; ETV4; TBL1X; ERG; WWP1; SALL1; SMARCB1; HOXB6; ZNF112; NR2E1; MEIS2; CDK2; NPM1; HHEX; DACH1; EHF; E2F2; TFEC; NR5A2; ARID5B; SOHLH2; UBE2B; WNT4; RORA; CNOT3; ATF4; ZNF304; NR2F6; HMBOX1; HIPK1; ZBTB18; ZSCAN31; EMX2; ARNT2; ZNF571; HMGA1; MED15; FOXF2; ATF3; ERBB4; CUX1; FOXF1; ELK3; CREG1; ZHX2; VPS72; RYBP; ZNF83; ETS2; TSC22D1; GLI2; MYBL1; SOX11; CEBPD; TRPS1; ELF3; RUNX3; NFE2L3; TOX3
Down-regulation 79 HMGA2; FOSL1; EGR1; NUP62; DRAP1; STAT1; CD3D; TCEB2; MAGED1; ZEB2; PRRX1; SAFB; EGR3; SIX1; MEF2C; SNAI2; BCL11B; EGR2; ZBTB24; HOXC10; TSC22D2; EED; ZMYM2; POLR2A; BCL10; TFAM; LMCD1; RBBP5; CTNNB1; ZNF160; TWIST1; MAX; JUNB; PMF1; TAF9; ATF1; HOXA10; BBX; THRAP3; ZNF430; VGLL4; RBBP4; ZNF721; ZNF652; MED1; TFDP2; SATB2; CRY1; ZNF611; HOXC6; EGR4; NCOR2; PTRF; NR4A1; TULP4; CITED2; NKX2-1; ETV5; EDF1; CARHSP1; FOXD1; ASCL1; PSIP1; HMGB3; TOX; POU2AF1; IRF4; SMARCA2; IRX5; MNDA; TBX2; MAF; AES; BHLHE41; ZIC1; HMGN3; PDLIM1; MSX1; KDM5A