Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21579	Cgp-60474	GSE70138	SKL.C	Human	24h	1.11uM	EID0066

Response Information :

Types	Number	Response transcription factors
Up-regulation	203	HOXC5; HIC2; MYRF; HOXD3; NFATC4; RBPJL; ZNF816; SOX17; DMTF1; ZNF75D; TFDP3; PHOX2B; HAND1; ZNF74; EGR1; ZNF536; ZFHX2; CREB3; BRD7; VENTX; MAML3; ZFPM2; HNF4A; CDX1; PPARG; FOXF1; ZNF423; NR1I3; THRB; EHF; GBX1; NR1I2; SHOX; ERBB4; MECP2; ZNF835; MAK; FOXJ1; ZNF154; FOXF2; MYBL2; PHOX2A; CERS6; ESR1; CHD2; ZNF507; NKX6-1; NFKB2; BRWD1; SIX3; GRHL2; KLF7; NR4A3; RING1; TLX2; CIITA; CARF; HNF1A; FOS; HMGXB3; MEIS1; SOX1; VGLL1; HIPK2; HOXB1; PPARA; PRDM12; PBX2; EYA1; AEBP1; MYT1; RARB; PROP1; RB1; PAX1; NEUROD1; MED12; NFIX; ARID3A; GATA1; KMT2D; HOXD9; SRCAP; OVOL2; WT1; EPAS1; REL; ISL1; LHX6; ZNF768; BNC1; CBFA2T3; NR0B2; WNT4; MYCL; MAPK8IP1; TGFB1; MMS19; NFKBIB; EMX2; HDAC5; PRMT2; ZNF264; MECOM; KDM4C; TCEA2; ZNF611; MED15; E2F5; SOX3; ZNF467; TCEB2; GATA6; TGIF2; TFDP2; SOX5; HIPK3; FOXI1; DLX4; SPDEF; PAX6; HHEX; MYCN; SUMO1; SMARCC1; ZNF652; HOXB5; ZNF91; OVOL1; SMAD6; TWIST1; L3MBTL1; MEIS2; CD3D; ZFP30; CREBL2; CSDE1; JUP; TOX; MEOX1; NR4A1; ZNF44; ZKSCAN1; BNC2; HIRA; YEATS2; GFI1B; CBX7; TCEA1; MTA1; FLI1; NR2E1; ST18; VPS72; EGR4; PDLIM1; NKX2-2; IRF6; NR5A2; SOHLH2; SIM2; MYBL1; NANOG; ZNF665; GTF3A; HOXC4; GFI1; IRF9; SNAI2; HOXD1; DACH1; FOXA2; INSR; ARNT2; OSR2; MITF; TAF9B; CARHSP1; ZBED2; ZSCAN18; FOSB; WWC1; HEY1; LITAF; ZNF589; CEBPD; TBX2; TFEC; NFE2L3; HMBOX1; KLF5; ATF3; INSM1; NR2F1; IKZF1; ID4; HOXB6; PITX1; ID1; ELF3; MAF; BHLHE41; SOX9
Down-regulation	188	HIF1A; ECD; FOSL1; HMGA2; NUP62; NFKBIA; TBPL1; HDAC2; TBP; FOXO3; CCDC59; HOXA5; XBP1; NR1H2; FHL2; SCAND1; CDK7; RORA; WWTR1; HOXA10; ZNF473; SFPQ; UBE2I; BATF3; BHLHE40; TLE1; TFAM; ZBTB11; KAT7; NRBF2; ZNF226; USP22; RBM14; BCLAF1; ZNF593; EED; DPF2; DDIT3; ARID4B; ZNF146; NFIL3; KLF2; CDYL; MED1; RBPMS; SIX2; POLR2A; BRD8; BLM; JUN; MYC; CRY1; SNIP1; KDM5D; ELK1; KAT8; SERTAD2; ETV1; HOXA7; CTR9; SUB1; BAZ1B; MEF2C; YBX3; ITGB3BP; NPAT; ADNP2; PHF20; SMAD3; ZBTB24; CTCF; ZFP64; PNRC1; TAF1A; MNT; HSF2; SIX1; MAX; PRDM4; EN1; ZNF302; TRIM28; NKX3-1; ING2; BRD3; TMF1; TSC22D4; SP110; MEF2A; SNW1; BTG1; PMS1; PPARGC1A; ZNF131; RYBP; UBP1; CARM1; ZNF432; BCL3; ETS1; ZNF84; RFX5; FOXE1; SPEN; ZNF148; CITED2; ARID4A; AFF1; ING3; MAGED1; SMARCA2; BASP1; ZZZ3; ZNF24; BCL10; MED7; SREBF1; DDX5; NFIB; CREB3L2; HMGXB4; NFKB1; RLF; KLF6; DNAJC2; RAN; FOXC1; HOXC10; PATZ1; TRIM32; SMARCE1; ZNF189; ZMIZ2; CHD1; ZNF267; RUVBL2; MED27; RERE; FOXO1; BBX; TAF7; LIMD1; ABL1; RBBP4; PIR; CRK; SMARCD3; APEX1; ADNP; PIAS2; ATF5; NKX2-1; TCF7L2; HOXC6; JUNB; IRX5; CEBPZ; ATF1; TGIF1; PUF60; RNF138; TOB1; RXRA; ENO1; TBL1X; SAP30; ATF4; PCGF2; ZMYND8; PEG3; RBPJ; ZBTB38; HTATIP2; NR1D2; NR2F2; TBX3; SMARCA1; HLF; BIRC2; TSC22D1; SUV39H1; KDM5A; HMGB2; MAFB; TRPS1; ZBTB18; ZIC1; MTF2