Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21570 Tivozanib GSE70138 SKL.C Human 24h 0.12uM EID0066
Types Number Response transcription factors
Up-regulation 37 MXI1; PTTG1; MSX1; NCOA1; PRRX1; PLAGL1; TAF10; KLF4; SMAD3; ZNF32; TCF7L2; PHIP; MEIS2; PSIP1; JAK2; MYCN; JARID2; PURA; RXRA; MAGED1; MYCL; KLF11; IRF1; ZMYND8; NRIP1; ZEB1; ZFP36L2; ID4; PEG3; HMGA1; ZBTB18; HEY1; ZIC1; EYA2; ZNF131; LEF1; TXNIP
Down-regulation 43 NR1H2; MED17; FOXF2; NR4A1; CREB3; FOXI1; HOXA10; MYRF; NKX2-1; FOXJ3; FOXE1; BASP1; HOXC10; SP3; BAZ2A; KDM5D; GRHL2; SMAD5; FOXA1; WWC1; TFCP2L1; PTRF; FOXF1; WT1; CRYM; KLF10; OLIG2; MYBL1; SMAD7; STAT4; HHEX; ATF1; TGFB1; IRX5; TOB1; VPS72; HOXD1; ETS2; NR1D2; CEBPZ; PBX1; E2F2; TRIM29