Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21567	Tivozanib	GSE70138	SKL.C	Human	24h	3.33uM	EID0066

Response Information :

Types	Number	Response transcription factors
Up-regulation	75	FOS; GATA3; MNAT1; COPS2; ID3; CEBPG; CREB5; PRMT2; ESR1; ZNF692; ZNF586; SIX1; MDM4; PTTG1; EYA1; BACH1; TDP2; TP63; USP16; TCF4; SIM2; DACH1; SFMBT1; TULP4; STAT2; MEOX2; RBBP5; EMX2; BACH2; ZFHX4; TCF12; ZNF264; SOX11; PPP1R13L; ZNF91; SIX3; SMAD6; HDAC9; NFIB; ERBB4; ZNF423; CENPF; JUP; ZNF430; POU4F1; KLF5; ISL1; ZNF544; ZFP36L2; KLF4; ZNF652; RBBP8; POU2AF1; SPDEF; CEBPZ; GTF3A; BIRC2; LITAF; NRIP1; ZNF302; CREG1; TGIF1; TRIM29; EYA2; MECOM; SMAD1; BCL11A; CALR; HMGA1; TBX3; TRPS1; IFI16; HEY1; MYB; ZNF131
Down-regulation	67	RUNX3; WT1; SFPQ; SMARCC2; NR4A3; NR4A2; ZNF267; E2F3; PLAGL2; BAZ2A; KLF10; CREM; HDAC1; FOSL2; RREB1; NR4A1; NEUROD1; NKX2-1; CNOT2; ERG; ZNF711; MED13; NCOR2; CD3D; MAGED1; ZNF165; FOXL2; FOXJ3; EGR2; SP2; E2F8; PRKDC; MED14; TCF20; NKX2-2; POLR2A; BHLHE40; MLXIP; EGR4; ZNF217; HOXA10; GATA4; MNDA; EGR3; ATF1; FOXC1; NCOA2; ZBTB20; PURA; LMCD1; IKBKAP; HMGN3; TGFB1; LPIN2; HOXC6; SATB2; ZBTB16; ZBTB38; ETS2; CDK2; IRF8; TOX3; NR2F1; ASCL1; TSC22D1; PIR; LEF1