Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21566 Tivozanib GSE70138 SKL.C Human 24h 10uM EID0066
Types Number Response transcription factors
Up-regulation 45 FOS; SOX4; NFIL3; DAXX; GLI2; LITAF; NEUROD1; TDRD3; NCOA6; FOXO3; PEG3; PLAGL1; FOXN3; NAB1; ZNF32; PRRX1; TAF1D; INSR; ZBTB38; BNC2; CARHSP1; AEBP1; SNAI2; CENPF; CHD9; CEBPD; PBX1; MXI1; MECOM; BMI1; MEIS1; NRIP1; TBL1X; KDM5D; NCOR2; POU4F1; PAX6; ZFPM2; ATF3; POU2AF1; FOXO1; NR1D2; ID4; MAF; TXNIP
Down-regulation 57 HOXB9; SALL1; EYA1; PSMC3IP; SUPT3H; NR1H2; HOXA7; STAT1; XRCC6; IRX5; SMAD6; ID3; NKX2-1; KLF1; ARNTL; TGFB1; HIRA; MTA2; JAK2; ZNF304; EGR1; SIX2; FOXA1; KLF2; HEY2; ID2; SIX1; CITED1; ZMYND8; HOXA10; SATB2; TBL1XR1; FOXG1; IRF9; HOXC10; CNOT3; HMBOX1; RBPMS; ZNF131; SOX9; JUP; WWTR1; RBBP4; EGR3; CALR; DACH1; ID1; AHR; ZHX2; HHEX; HMGN3; CRYM; NFIB; HTATIP2; ASCL1; PDLIM1; E2F2