Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21553	Mitoxantrone	GSE70138	SKL.C	Human	24h	10uM	EID0065

Response Information :

Types	Number	Response transcription factors
Up-regulation	44	GLI2; TBPL1; FOXM1; HMGA1; ARL2BP; RBBP8; ESRRG; SHOX2; SIX3; ISL1; TCEA1; PPP1R13L; KDM5A; MBD2; POLR3C; EMX2; BNC2; TGFB1I1; FOXN3; NR5A2; CDK2; SOX17; ZNF423; ATN1; RBPMS; MEIS2; ARNTL2; LIN28A; MNDA; PAX6; VGLL1; TRIM29; EYA2; SNAI2; IRF6; INSR; NEUROD1; NR2F1; ST18; ARNT2; ZBED2; MECOM; EHF; PDLIM1
Down-regulation	93	MYC; CDK7; BHLHE40; ERBB2; NFKBIA; MTF2; NFIL3; MEF2C; KAT6A; NRIP1; ZBTB11; ARID4B; KDM5B; HOXA10; FOSL1; JUN; MED17; TBP; VGLL4; MED13; HOXA5; EGR1; ZMYM2; NR0B1; KAT8; JUNB; RLF; NR3C2; FOXJ3; TAF1D; PLAGL2; BRD8; BTG1; VEZF1; ARID5B; HBP1; ADNP; SERTAD2; BCL3; MED1; NUP62; ZNF12; ZBTB1; ZKSCAN1; REST; ZNF107; MKL2; IRF2; BRPF1; BATF3; IFI16; CREM; SIX1; FOSB; FOXA1; NLK; FOXC1; EGR2; SMARCC2; PAXBP1; KLF10; ZNF84; KLF6; RYBP; EGR3; BCOR; THAP11; ZNF160; BAZ2B; TGIF1; RUNX3; CREB3L2; MXI1; KLF2; ZBTB43; RORA; LEF1; ZMYND8; NR4A2; CITED2; TOB1; ZNF652; TSC22D1; ERG; NFATC3; NKX2-1; CREB1; HOXC6; ASCL1; PEG3; TOX3; SUV39H1; NR3C1