Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21511	Osimertinib	GSE70138	SKL.C	Human	24h	3.33uM	EID0065

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	TP53; CEBPD; NFIL3; ZZZ3; SIM2; E2F2; ZNF7; ZNF219; CARHSP1; TBP; ID2; PAX6; TAL1; MEIS1; PKNOX1; EMX2; ZFP36L2; NRBF2; CDK9; INSM1; DBP; RBBP4; ZNF623; COPS2; VGLL1; PFDN5; MITF; BTG1; ACTL6B; ARID5B; MYCN; SAP30; HSF1; SPEN; EPAS1; HMGN3; ZNF189; MYRF; YBX1; CREBL2; ELF4; CTNNB1; FOXE1; ZNF43; HEY1; TFAP2A; WNT4; TXNIP; INSR; WT1; EGR2; STAT1; ETS2; TP63; TLE4; TBX3; EHF; BHLHE41; ATF5; HOXC6
Down-regulation	64	HMGA2; RUVBL1; MYC; MYCBP; BCL3; ETV1; SFPQ; FOSL1; ZBTB18; RBM14; REST; MAGED1; CHD9; RARA; YWHAB; SP3; NFYA; ZMYM2; VEZF1; ZMYND8; CBFB; SIX1; EGR1; HOXB2; C1QBP; IFI16; TGFB1; ZNF107; PDLIM1; CHD7; PRRX1; TWIST1; IRF8; JARID2; GTF3A; NFE2L3; ELK3; KLF6; SOX11; EYA1; SSX1; FOSB; IRF7; TCF7; YBX3; NKX2-1; ZNF423; EGR3; POU2AF1; ESR1; LEF1; RUNX3; BMI1; ELF3; NR4A2; TGFB1I1; SMAD7; ZFPM2; AEBP1; MECOM; NFATC3; MYBL1; CREB1; NR3C1