Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21510	Osimertinib	GSE70138	SKL.C	Human	24h	10uM	EID0065

Response Information :

Types	Number	Response transcription factors
Up-regulation	95	TSC22D3; NCOA3; HBP1; MAFB; PPARD; ETV1; CEBPD; HIVEP1; NFIL3; PPP1R13L; RBBP5; HMGA1; FOXD1; ZNF281; NUP62; SP100; BHLHE40; DBP; RSF1; SOX13; BRIP1; NFKBIA; ADRB2; SP110; INSR; FOXO3; TWIST1; BRD4; BAZ1B; PLAG1; MDM2; NFYC; BTG1; TCEB2; CXXC1; SATB2; ID2; MYCL; SAP30; KLF11; NR3C1; ZFHX3; ZEB1; L3MBTL1; BPTF; MNDA; ZHX2; PBX3; GATA6; AFF1; ZNF580; CERS4; ZNF467; LIN28A; TSC22D1; GATA3; PHF1; NR5A2; PURA; BCL6; ERBB4; STAT1; KLF9; BANP; PFDN5; PHIP; ZNF331; MBD2; TBX2; SALL1; TRIM22; HTATIP2; IRF7; MYB; MEIS2; SPIB; MECOM; RXRA; REPIN1; ZNF423; ZFP36L2; CHD7; ASCL1; BASP1; IRF4; THAP11; ETV5; LITAF; PBX1; TP63; TOB1; SOX9; CITED2; CREB1; HEY1
Down-regulation	56	RUVBL1; MYCBP; EZH2; MEF2C; HDAC2; MYC; RNF141; ECD; CCNE1; URI1; ZNF239; SMARCE1; WDR77; ZBED4; RAN; MED21; HMGB3; SUB1; NR0B1; EYA1; WWTR1; CCNA2; BCL11B; ILF2; NKX3-1; CEBPG; UBP1; ZNF32; MLXIP; PRKDC; NR4A1; ZNF84; BCLAF1; SFPQ; ZNF22; EGR1; NFIB; CDK2; MAGED1; NKX2-2; CCNC; C1QBP; SIAH2; GRHL2; YBX3; ZEB2; EGR3; PLAGL1; DACH1; ZSCAN18; EGR2; BAZ1A; CTBP2; MYBL1; NFATC3; SUV39H1