Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21501 Motesanib GSE70138 SKL.C Human 24h 0.37uM EID0065
Types Number Response transcription factors
Up-regulation 59 HSF2; KAT8; ING3; ZBTB16; ZBTB18; ZNF652; SUV39H1; PHF8; FOXG1; KLF9; ARID4A; MAK; TTF1; ADRB2; HBP1; ZNF200; ZNF292; NR1D2; RBL2; HES1; KDM5A; TGIF1; ZNF184; ZNF430; SMAD3; HDAC5; XRCC6; ELF4; ZNF468; BRD3; MAZ; CALR; PHIP; BCL3; HOXB13; LITAF; MAF; BBX; ZNF217; PQBP1; HIVEP2; TSC22D1; ZHX2; CD3D; SOX17; BCL10; ID3; REPIN1; OSR2; FOSL2; HLF; NEUROD1; TXNIP; NR2F2; TOB1; KDM5D; BAZ1A; HEY1; NFATC3
Down-regulation 44 SOX4; KLF6; DNAJC1; TCEA1; HLTF; ZNF266; SUB1; KLF13; ZNF532; ATF5; RBPJ; FOXL2; HMBOX1; NPAS2; PRKDC; NFYA; FOXF2; PPARGC1A; IRF7; KLF7; RUNX1; BRD4; SHOX2; DNMT3B; DMTF1; HMGN3; PURA; ZEB1; NR0B1; FOSB; RBPMS; ZBED2; IFI16; MAFB; WT1; SOX11; HOXB6; SOX9; ZSCAN18; EGR2; ESR1; DACH1; CREB1; E2F2