Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21500 Motesanib GSE70138 SKL.C Human 24h 1.11uM EID0065
Types Number Response transcription factors
Up-regulation 65 MNAT1; KLF11; E2F2; AES; RBBP4; ZNF160; SIAH2; IKBKAP; MYT1; MTA2; INSM1; ZNF611; MYB; BTG1; TAF9B; IRF1; ZNF177; DBP; PTTG1; RUNX1; KLF4; ZNF721; FOXN3; TLE2; FOSB; CSDE1; ST18; TXNIP; ZNF665; TCF12; MEIS1; PNRC1; ZNF189; HOXB6; HIVEP2; SIX1; ZNF165; RBPMS; EMX2; ZNF83; NKX2-2; ZSCAN31; PBX1; ZKSCAN1; OSR2; DNMT3B; TRIM16; PBX3; PAX6; KLF5; ZNF91; ZBTB38; BCL11A; PLAGL1; MSX1; TRIM22; KDM5D; SMARCD3; CREB1; BASP1; ASCL1; TBX3; ZSCAN18; HEY1; PDLIM1
Down-regulation 47 NRIP1; PHOX2B; RNF6; ZNF195; CD3D; CDC5L; GTF3A; CBX6; ERF; HMGB1; DNAJC2; FOXG1; CUX1; RUNX3; ZNF217; CUX2; KLF9; KLF7; MAFG; NR4A3; POU2AF1; MKL2; EYA1; MYRF; STAT5A; KAT2B; TRIB3; EGR2; ERBB4; ZNF423; FOXO1; ELF3; STAT4; HLF; PQBP1; ZNF331; HIC2; NFE2L3; HIRA; TRPS1; ATF3; MECOM; IRF4; ETV5; NFATC3; ZFPM2; SUV39H1