Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21499 Motesanib GSE70138 SKL.C Human 24h 3.33uM EID0065
Types Number Response transcription factors
Up-regulation 50 ISL1; HAND1; SAP30; ZNF430; EMX2; PITX1; PFDN5; DEK; ZNF528; RBFOX2; ZNF665; ZFP36L1; MYT1L; ZNF552; ZNF611; SMAD3; PGR; ZNF91; TOX; NR1H4; EGR3; FOXF1; ZNF136; EGR1; MEIS1; ZKSCAN1; TDP2; TP63; ZEB2; PBX1; ZFHX4; ZNF264; SALL1; NANOG; KDM5D; ETS2; ID4; SOX11; MNDA; TRIM29; MECOM; BASP1; INSM1; CREB1; KLF5; ID3; HEY1; CRYM; PEG3; PDLIM1
Down-regulation 32 AEBP1; SLC2A4RG; LMCD1; IRF7; HTATIP2; REST; BAZ2A; CRY1; SAP18; KAT6B; BRD2; RUNX1; TRIM24; HOXC6; BATF3; IRX5; CBFB; WWTR1; ETV5; CERS6; TRIB3; KLF6; HOXC10; SIX1; MYRF; IRF4; FOXC1; BMI1; NFATC3; HOXB2; TOX3; NR3C1