Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21482 Gsk-1059615 GSE70138 SKL.C Human 24h 1.11uM EID0065
Types Number Response transcription factors
Up-regulation 91 TSC22D3; TCEA2; CEBPD; KLF11; RB1; HBP1; ZNF23; NFATC4; CEBPA; MYB; INSR; BRD8; STAT5B; HDAC6; RBM39; ZNF219; MXI1; RLF; HOXB7; ASXL1; BRD2; UBE2B; LYL1; HOXA5; RNF14; NFE2; EMX2; FOXO3; TDP2; STAT6; TGIF1; MTA1; HIPK1; FOXD1; SETDB1; KLF9; MMS19; CREBL2; PPP1R13L; OSR2; ARID5B; RNF138; KLF7; PFDN5; HDAC5; BRD4; ST18; PHF1; TGFB1I1; TLE2; INSM1; PHF20; FOXM1; ZNF423; TFEB; PLAG1; POU4F1; TULP3; ZNF665; PNRC1; HSF1; TFDP2; TXNIP; RREB1; ZNF302; CNBP; RBPMS; KLF1; TAL1; KLF4; GATA6; TOB1; BCL11A; JUP; ZFP36L2; EHF; NEUROD1; MEIS1; PAX5; SMARCA1; ZNF281; ZNF83; AFF1; TSC22D1; TFAP2A; PLAGL1; ZIC1; BASP1; HOXC6; CITED2; PDLIM1
Down-regulation 69 RUVBL1; MEF2C; MYCBP; WDR77; BHLHE40; GTF2A2; ETV4; NFIL3; HDAC2; PARP1; CALR; PKNOX2; SFPQ; ERBB2; RBM14; SOHLH2; DNAJC1; PRKDC; TAF1D; EGR2; EGR3; POLR2A; LZTS1; SOX2; CD3D; SSX1; RBPJ; MEOX1; ZNF551; SUB1; HMGB3; ZBTB20; BATF3; DMTF1; MKL2; BAZ2A; FOSL2; SOX9; MED1; NR2F2; NPAS2; SIX2; NR1I2; C1QBP; ID1; FOXC1; TRIB3; EYA1; NR4A2; SIX1; MEIS2; MNAT1; HOXC10; PIR; ID4; TOX3; HIC2; TCF4; NFE2L3; ID3; WT1; PBX3; MAF; NFATC3; STAT4; MYBL1; HEY1; SUV39H1; NR3C1