Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21481 Gsk-1059615 GSE70138 SKL.C Human 24h 3.33uM EID0065
Types Number Response transcription factors
Up-regulation 120 TSC22D3; CEBPD; TBPL1; HMGA1; TCEA2; NFIL3; AGO2; CDK9; FOXK2; FLNA; NFATC4; STAT5B; HINFP; HBP1; HSF1; KMT2B; ZNF16; KLF11; FOXO3; ZNF7; ZNF34; CBX4; ASXL1; HOXA5; FOXM1; MED15; UBE2B; HDAC5; ATF7IP; TRIM28; KLF7; ZBTB48; MTF1; ZNF250; PPP1R13L; DEK; TRAK1; BACH1; ZHX2; EP300; HOXC4; SPEN; TAF1C; CIZ1; FOXD1; ZNF623; KLF9; PRMT2; MKL1; ZNF331; ATF4; ATF2; SP100; BACH2; SIRT7; ZNF589; INSM1; CEBPG; BRD4; TFDP2; RCOR3; IRF5; CCNE1; CBX6; ZNF500; ZNF131; MXI1; KLF13; TERF2; STAT6; SALL1; COPS2; TDP2; MNT; ZNF165; TLE1; VDR; INSR; HOXB7; CRY1; RBBP8; ZEB2; PNRC1; JUND; ZNF580; JUP; KAT2B; PAWR; TFEB; EZH1; TOB1; BCL11A; DDX17; DLX5; NFE2L2; PITX1; SOX10; TGIF1; TRPS1; CNBP; TP63; HOXB6; TRIM29; MEIS1; MECOM; NEUROD1; EHF; EMX2; EYA2; PAX5; SPIB; THAP11; PAX6; MSX1; CRK; RELB; NR4A2; MYBL1; PDLIM1; NFATC3
Down-regulation 83 RUVBL1; MYCBP; MEF2C; ECD; VGLL4; GTF2A2; ERBB2; HIF1A; AR; SMARCD2; WDR77; CD3D; SFPQ; FOXA1; TAF9B; SUB1; EGR1; IL16; CUX2; ATF5; STAT1; SOX11; MNAT1; AES; EGR3; RNF6; ZMYM2; RUNX1; ZBED2; LMCD1; ZEB1; REST; SAP18; HMGN3; EGR2; ATF3; ADRB2; CREB3L1; NANOG; WWC1; CBFB; SMAD3; TCF4; NFE2L3; SOX9; C1QBP; ID2; RBPJ; JAK2; BCLAF1; BASP1; MAGED1; ELK3; AEBP1; CREB3L2; PTRF; DDX5; LOXL2; YWHAB; CBFA2T3; KLF2; ETS2; LEF1; CITED1; NKX3-1; ZMYND8; CRYM; FOXE1; SIX1; IRX5; BHLHE41; TFAP2C; TRIM16; ZIC1; AHR; SMAD7; ERG; DACH1; TBX3; ID1; NR3C1; ESR1; SUV39H1