Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21475 Bms-777607 GSE70138 SKL.C Human 24h 3.33uM EID0065
Types Number Response transcription factors
Up-regulation 68 PFDN5; PIAS1; CEBPZ; ZHX2; ZNF133; POU4F1; SMAD3; RUVBL2; SUV39H1; DLX4; GFI1; IFI16; TAF5; OSR2; BLM; NUP62; BRF2; KAT8; STAT6; HMGB1; ZNF410; PREB; WWTR1; NR3C1; GTF3A; IRF2; DDX17; KLF3; THAP7; LYL1; NCOA4; ASH2L; NR0B1; NR1H4; EN1; HOXA1; ZNF107; MED23; HOXA5; CREB3L2; GATA6; EMX2; E2F8; FOXO1; TCF7L2; HDAC1; TCF21; ZFP36L2; TBX3; MXI1; SSX1; ZEB2; TFAP2C; NEUROD1; SMAD7; MEOX2; POU2AF1; NR2F2; HHEX; TBL1X; SMAD6; MEIS2; SNAI2; ESR1; ARNT2; CRYM; MSX1; PDLIM1
Down-regulation 46 ERBB2; SOX4; LMCD1; IRF7; ATF5; AEBP1; UBE3A; SSBP2; KLF6; POLR2A; RCOR3; ENO1; FUBP1; SREBF2; CREG1; MTA1; CBX3; JUND; TOB1; MXD4; PBX3; EPAS1; HMBOX1; HMGB3; CERS6; HMGN3; RAD21; RUNX3; GTF2I; ZBTB18; HOXB6; ZMYND11; MED1; TSC22D1; CTBP2; MAFB; MAF; TGFB1; SOX11; ETS2; INSM1; SOX9; NFATC3; BHLHE41; MEIS1; DACH1