Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21469 Doramapimod GSE70138 SKL.C Human 24h 3.33uM EID0065
Types Number Response transcription factors
Up-regulation 53 PCGF2; AATF; GATA6; ZNF292; MED1; ZBTB18; CENPF; EGR1; GATA3; CBX7; ING3; CEBPZ; PTTG1; AIP; LMCD1; KLF2; RBBP7; NELFB; E2F8; TRIM32; KLF11; PATZ1; APEX1; TOX; HOXA5; PHIP; HOXB7; ZNF93; NFIB; INSR; ZNF529; BCL6; NR2F2; SOX11; ASCL1; ZNF91; RXRA; ELF5; EMX2; MAGED1; ELK3; PLAGL1; KDM5D; TOB1; NFE2L3; TSC22D1; CREB1; NKX2-2; MAFB; PBX3; ERG; PEG3; TXNIP
Down-regulation 75 DNAJC1; KLF13; IRF1; NRIP1; VGLL4; SFMBT1; ETV7; DLX4; FOXO4; WDR77; RREB1; KLF5; TGIF2; FOXF2; NR1I2; ARID5A; CALR; PEX2; CNOT3; EYA1; GATA1; DLX2; NFKB1; TDP2; ZSCAN31; CDX1; KLF1; PRDM1; SF1; BNC1; SOHLH2; UBP1; ZBED2; TFDP2; KAT2B; MEIS1; JUND; ZNF580; FOXA1; SSBP2; KLF3; SIX2; FOXF1; TRIM22; CRYM; RUNX1; VDR; PAWR; SP140L; CAMTA1; HOXB2; SNAI2; IFI16; NFE2; NKX2-1; FOSB; DACH1; KLF9; LPIN2; ID3; HOXC10; TRIB3; TGFB1; EHF; TP63; ESR1; PAX6; IRF6; SMAD7; NFATC3; SOX9; ZSCAN18; BASP1; NR3C1; E2F2