Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21468	Doramapimod	GSE70138	SKL.C	Human	24h	10uM	EID0065

Response Information :

Types	Number	Response transcription factors
Up-regulation	131	TBX2; SALL2; TCF20; KDM5D; TRIP6; ZFY; TCF7L2; ZNF32; PBX3; FOXJ3; ISL1; ZNF22; KMT2A; TAF7; TRIM25; GCFC2; STAT6; EMX2; HOXB6; KMT2D; KLF11; PRDM4; ERBB4; ZNF562; CHD8; MXD1; ZNF44; ZKSCAN7; CUX2; OSR2; SMARCA2; ING3; FOSL2; RSF1; PRKDC; NPAT; PRRX1; FHL5; ZNF10; OVOL2; APEX1; MAGED1; ARID4A; ZNF117; E2F3; ZNF426; TXNIP; MED13; SP2; PPP1R13L; RERE; ZNF136; MMS19; PLAGL1; DEAF1; RXRA; NR0B1; MSX1; GRHL2; POU4F2; DLX5; AEBP1; NKX2-2; NCOR2; ZIC3; GATA3; NR1D2; KLF7; SIM1; BACH1; ADNP2; PBRM1; ANKRD1; HOXB7; TTF2; FOXN3; BCL11B; AR; WT1; ZNF432; MYB; PREB; NR2F2; NFAT5; NR4A3; MEOX2; ZNF43; SOX17; ZIC1; TCF7L1; RBBP8; RCOR1; AFF1; BCL6; PITX2; JUNB; SERTAD2; LMCD1; ZSCAN31; CREB3L1; ST18; MEIS1; NRBF2; JARID2; KLF10; GATA6; NR4A2; ERG; ZBTB16; ZNF165; ZBTB18; ZNF264; MECOM; HOXC6; AHR; ZFP36L2; ZNF423; CRYM; ETS2; NEUROD1; CTBP2; LEF1; INSR; ZEB2; PAX6; ZSCAN18; KLF2; KLF5; NFATC3; ESR1; HOXB2
Down-regulation	82	BRD2; CEBPD; PHF1; PTTG1; TGIF2; IRF8; RNF111; FOXD1; WWTR1; BCL3; NFYB; DNAJC1; FOXO4; ARNTL; CREM; NPAS2; BTAF1; RNF14; NR2F6; MEF2C; SOX10; MYRF; CDYL; CARHSP1; PAX5; AIP; SAFB2; BCL11A; RUNX3; TULP4; RBPJ; RNF6; MBD2; KAT2B; MKL2; BBX; SMARCB1; HMGB3; ZNF24; POU2AF1; RBL2; BAZ1A; HIRA; DMTF1; TGIF1; ZBTB1; MED23; FOXO1; SATB2; THAP10; CCNC; CREBL2; HMGA1; HLTF; PDLIM1; TCF4; ZBED2; FOXF1; SMAD1; FOXE1; IRF4; DDIT3; PHIP; TLE4; ZMYND8; BASP1; HSBP1; LOXL2; IRF7; ID4; ELK3; NR1H2; MYBL1; TOX; HHEX; TFAP2A; STAT1; LITAF; TOX3; ASCL1; DAXX; NR3C1