Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21462 Ast-1306 GSE70138 SKL.C Human 24h 10uM EID0065
Types Number Response transcription factors
Up-regulation 49 TP53; NFIL3; MXI1; TXNIP; ZNF133; RCOR3; GTF2IRD1; STAT5A; VDR; SPEN; CREBL2; MITF; WWP1; PIR; NR3C2; NFE2L1; ZNF266; ELF5; GRHL2; STAT3; CREB3; PITX1; SATB1; MAF; PBXIP1; AEBP1; CALR; TOPORS; CREG1; REPIN1; NR1H2; ZBTB16; PITX2; ATF3; TRIB3; HOXC6; TOB1; NR1D2; WNT4; ZNF331; BHLHE41; BCL6; GATA6; MAGED1; LPIN2; SPIB; NR4A2; STAT1; PDLIM1
Down-regulation 71 MYCBP; TLE1; EGR1; CRK; BRD4; MED24; DNAJC1; CUX2; RLF; BCL3; ZNF430; ZMYM2; ATF5; KLF7; PPRC1; POLR2A; KLF13; FOSL1; RARA; USP16; STAT6; NPAS2; ERF; MYCN; OLIG2; ETV4; UBP1; SUB1; ASCL1; CHD9; KLF6; CDYL; RBPJ; BACH2; ATF7IP; MYRF; BMI1; RFX5; BASP1; EGR3; ZBED2; TCF12; RYBP; LMCD1; PTRF; SFPQ; EGR2; SERTAD2; DLX2; HEY2; MYCL; ELK3; FOSB; HTATIP2; NCOA1; ZEB1; ZFP36L2; TRPS1; ZNF652; YWHAB; BAZ1A; HLF; DACH1; HOXB2; ZNF423; SOX9; TOX3; NFATC3; CREB1; ESR1; SUV39H1