Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21458 Ibrutinib GSE70138 SKL.C Human 24h 1.11uM EID0065
Types Number Response transcription factors
Up-regulation 75 BTF3; PEG3; GATA6; ISL1; SP100; ZNF573; IRF8; ZNF165; TCEB2; ERBB4; DAXX; SP110; ZNF571; WT1; ATF3; BANP; NR3C1; SSBP2; STAT5A; KDM5A; CD3D; MITF; NR1D2; KLF6; ID4; SOX17; GATA3; LMCD1; ID1; CSDE1; FOXN3; TCF7; TWIST1; APEX1; ZFP36L2; ELF4; HIVEP2; AEBP1; ID2; GATA4; KLF9; ZBED1; MEIS1; ZSCAN31; ZBTB38; PIR; OSR2; TRIM22; IRF9; IRF7; MEOX2; SNAI2; ZFPM2; TBX3; MAGED1; DNMT3B; LEF1; ZNF652; TCF4; MECOM; PBX1; KLF2; MXI1; MEIS2; HEY1; PBX3; ZNF423; RUNX3; TLE4; MAF; TRIM29; TP63; TXNIP; FOXF1; NFATC3
Down-regulation 63 HMGA2; MED17; MED25; ZNF274; TRIM28; CNOT2; FOXI1; ZBTB11; ZBTB7A; TAF6; NLK; MKL2; FOSL1; SATB2; IRF3; ATF5; STAT1; SAP30; HOXA11; NPAS2; ENO1; CRY1; CIZ1; E2F5; KLF15; RNF6; ZMYM2; EGR1; ZNF107; FOXG1; MED16; ZNF593; SMARCA5; DPF2; SALL1; NR2F1; ARNTL2; SIX1; POU4F1; SIX2; RNF138; POU2AF1; SSX1; LOXL2; VDR; AFF1; TGIF1; SERTAD2; ZNF580; FOXE1; IRF4; ELK3; CTR9; DLX2; EGR2; BAZ2B; NFE2L3; SOX9; EYA2; BAZ1A; BASP1; CREB1; ZNF586