Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21410 Tivozanib GSE70138 SKL.C Human 24h 0.12uM EID0065
Types Number Response transcription factors
Up-regulation 15 GATA2; TBX2; TGFB1; KLF9; HMGN3; ZMYND8; BMI1; MECOM; TRIM16; TSC22D1; PLAGL1; CITED2; AHR; HEY1; NFATC3
Down-regulation 34 HMG20B; BACH2; NR3C2; BTG1; MED13; PDLIM1; MED23; ZNF189; SOX10; OLIG2; POU4F1; SMARCA1; ZNF516; ZNF22; KLF6; KLF10; IRF6; INSM1; NKX2-2; TBX3; HOXD1; TOX3; BASP1; EGR3; NKX2-1; PEG3; DAXX; BAZ1A; CREB1; GATA3; ESR1; SUV39H1; E2F2; NR3C1