Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID21406 Tivozanib GSE70138 SKL.C Human 24h 10uM EID0065
Types Number Response transcription factors
Up-regulation 38 NFIL3; CEBPD; ARID5B; IRF1; CIZ1; HIPK1; EGR1; RUNX1; SATB1; ZNF593; ID2; GTF3A; TRIP6; INSR; MLXIP; DDIT3; HIVEP2; FOSB; IFI16; MAFB; FOXO1; HOXB7; NCOR2; FOSL2; TRIM16; ATF3; BMI1; BHLHE41; PIR; ELK3; AFF1; KDM5D; POU2AF1; MNDA; TGFB1I1; LEF1; MECOM; MSX1
Down-regulation 30 MYCBP; MEF2C; NR2F6; HMGB3; ENO1; YEATS4; SPIB; PAX5; MYBL1; MED14; HMGB2; ZBTB20; BTG1; TXNIP; TRPS1; ZBED2; IRX5; HOXC10; JUP; SMARCA1; IRF6; BASP1; TOX3; NFATC3; ID1; DACH1; PEG3; ESR1; GATA3; E2F2