Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID21393	Mitoxantrone	GSE70138	SKL.C	Human	24h	10uM	EID0064

Response Information :

Types	Number	Response transcription factors
Up-regulation	81	ZNF586; EMX2; IKZF1; CNOT3; ESRRG; HOXB6; ZNF419; TCEA1; ZNF134; ZNF132; HOXC5; PSMC3; ZNF551; ZNF91; HOXB5; ZNF350; ZNF580; TCF3; ZNF304; TCF21; ZNF224; HMGB1; ZNF606; CNBP; ZNF415; NR5A2; ZNF587; GATAD2A; KLF13; ZMYND11; HOXC4; DBP; LPIN2; MEIS1; SMAD2; HAND1; ZIC3; PBX3; BARX1; FOXM1; FOXL2; PHOX2B; HOXC10; ZNF22; NEUROD1; ZNF329; PPARGC1A; CREB3L1; TFAP2A; ERBB4; MECOM; DACH1; ESR1; DLX5; PRRX1; ZNF83; SMAD6; FLNA; ZFPM2; FOXF1; AR; SMAD4; SOX17; PLAG1; CDK2; PAWR; HMGA1; HOXB2; TGFB1I1; NANOG; MYBL1; MNDA; KLF5; CRYM; MYT1L; BASP1; INSM1; TXNIP; NFATC3; HOXC6; KDM5D
Down-regulation	89	MYC; NFKBIA; CDK7; BHLHE40; MEF2C; FOSL1; JUN; HMGA2; MTF2; FOXO4; AHR; SOX4; STAT1; CCNA2; ARID5A; TSC22D1; ARID5B; HOXA5; NUP62; FOSB; EGR1; BRPF1; ETV5; ARID4B; CEBPD; HSF2; BAZ2B; ILF2; NRIP1; EGR3; HHEX; GTF2IRD1; FOXC1; JUNB; EGR2; SOX10; SMARCD3; ZNF512B; HOXA10; ATF3; IRF1; BCL10; KLF6; ZNF184; NR1H3; E2F6; ZFHX4; ZMIZ1; CBX3; RBBP4; ZNF267; CITED1; SIX1; ZFP36L2; ZNF160; NFIB; NR4A1; YBX3; IRF7; BACH2; SIX2; MAGED1; TRIP6; ZEB2; POU2AF1; NKX3-1; PLAGL1; SOX11; TSC22D2; ZNF721; CTR9; KLF4; ZNF165; HLTF; ZKSCAN1; MLXIP; KLF11; KLF10; FOSL2; BAZ1A; SUB1; SMARCA2; TFAP2C; WWTR1; IFI16; HES1; ELK3; SUV39H1; NR3C1